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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Agriculture / Faculty of Agriculture >
Peer-reviewed Journal Articles, etc >
A soluble flavonoid-glycoside, alphaG-rutin, is absorbed as glycosides in the isolated gastric and intestinal mucosa.
| Title: | A soluble flavonoid-glycoside, alphaG-rutin, is absorbed as glycosides in the isolated gastric and intestinal mucosa. |
| Authors: | Matsumoto, Megumi Browse this author | | Matsukawa, Noriko Browse this author | | Mineo, Hitoshi Browse this author | | Chiji, Hideyuki Browse this author | | Hara, Hiroshi Browse this author →KAKEN DB |
| Keywords: | αG-rutin | | flavonoid-glycoside | | absorption | | Ussing chamber | | gastrointestine |
| Issue Date: | Sep-2004 |
| Publisher: | Japan Society for Bioscience, Biotechnology, and Agrochemistry |
| Journal Title: | Bioscience Biotechnology and Biochemistry |
| Volume: | 68 |
| Issue: | 9 |
| Start Page: | 1929 |
| End Page: | 1934 |
| Publisher DOI: | 10.1271/bbb.68.1929 |
| PMID: | 15388969 |
| Abstract: | We investigated the absorption and metabolism of the highly soluble quercetin glycoside αG-rutin, a glucose adduct of insoluble rutin, using the isolated mucosa of the rat stomach and intestines equipped with the Ussing chamber. αG-rutin and rutin appeared in the serosal sides of the gastric body and all the intestinal mucosa after the addition of αG-rutin (1 mM) to the mucosal fluid. The degree of αG-rutin appearance was much lower in the gastric fundus than in the other parts. Quercetin was not found in the mucosal fluid of any mucosal specimen. The concentrations (μM) of αG-rutin and rutin in the serosal fluid as a result of transport from the mucosal side increased time-dependently and linearly with mucosal αG-rutin concentration (1, 10 or 100 mM). The highest transport was shown in the ileal mucosa. These results indicate that αG-rutin is partly hydrolyzed to rutin through the intestine and absorbed as such. |
| Relation: | http://www.jstage.jst.go.jp/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/15855 |
| Appears in Collections: | 農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 原 博
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