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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Agriculture / Faculty of Agriculture >
Peer-reviewed Journal Articles, etc >
Dietary branched-chain amino acids suppress the expression of pancreatic amylase mRNA in rats.
| Title: | Dietary branched-chain amino acids suppress the expression of pancreatic amylase mRNA in rats. |
| Authors: | Hashimoto, Naoto Browse this author | | Hara, Hiroshi Browse this author →KAKEN DB |
| Keywords: | pancreatic amylase | | dietary branched-chain amino acids | | dietary carbohydrate | | rat |
| Issue Date: | May-2004 |
| Publisher: | Japan Society for Bioscience, Biotechnology, and Agrochemistry |
| Journal Title: | Bioscience Biotechnology and Biochemistry |
| Volume: | 68 |
| Issue: | 5 |
| Start Page: | 1067 |
| End Page: | 1072 |
| Publisher DOI: | 10.1271/bbb.68.1067 |
| PMID: | 15170111 |
| Abstract: | Regulators for pancreatic amylase were examined. Rats were fed ad libitum a 20% amino acid (AA) mixture diet (Con), a 60% AA diet (HA), a branched-chain amino acid (BCAA)-rich diet (BC), or a diet supplemented with AA other than BCAA (OA) for 7 d, or fed the Con, HA, BC diets or diets supplemented with individual BCAA. Activity and mRNA levels of pancreatic amylase in the BC and HA groups were lower than those in the Con and OA groups. Leucine and isoleucine contributed to these effects of the BC diet. The mRNA levels correlated with individual pancreatic BCAA concentrations but not with plasma insulin level. In conclusion, dietary BCAA, especially leucine and isoleucine, may reduce amylase mRNA and activity in rats. |
| Relation: | http://www.jstage.jst.go.jp/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/15857 |
| Appears in Collections: | 農学院・農学研究院 (Graduate School of Agriculture / Faculty of Agriculture) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 原 博
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