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Volume 2, Number 4 >

PRELIMINARY INVESTIGATIONS ON COMPLEMENT-FIXING ANTIGENS IN BOVINE TUBERCULOSIS

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Please use this identifier to cite or link to this item:https://doi.org/10.14943/jjvr.2.4.157

Title: PRELIMINARY INVESTIGATIONS ON COMPLEMENT-FIXING ANTIGENS IN BOVINE TUBERCULOSIS
Authors: SHIMIZU, Kiheiji Browse this author
Issue Date: 31-Jan-1955
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 2
Issue: 4
Start Page: 157
End Page: 167
Abstract: The principal subject discussed in the present paper is the antigenicities of several kinds of antigens for the C. F. T. in bovine tuberculosis. 1. The antigenicities of next-mentioned human and bovine type of antigens were examined ; Boiling supernatant, bacterial carbohydrate, bacterial protein, ether-extracted, ether-alcohol-extracted lipoids which were prepared from the dried bacilli preliminarily inactivated by temperature of 70℃ and 100℃, and tuberculin. 2. The boiling supernatant antigens from the human type bacilli by low temperature inactivation and from the bovine type bacilli inactivated by both low and high temperature, equally indicated very good antigenicity and specificity. 3. Bacterial proteins possess considerably good antigenicity, however, their reaction ranges was not so wide but that they easily lost their antigenicity by comparative low dilutions. 4. Tuberculin also indicated excellent antigenicity but the nonspecific reactions were sometimes recognized. 5. Ether-extracted lipoid antigens are not recommendable ones on account of their weak antigenicity, especially in the one from bovine type, and on account of non-specific reactions. 6. Bacterial carbohydrate antigens do not have any antigenicity at all.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/1663
Appears in Collections:Japanese Journal of Veterinary Research > Volume 2, Number 4

Submitter: 獣医学部図書室

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