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STUDIES ON HEPATITIS CONTAGIOSA CANIS I. : INFECTION EXPERIMENTS ON DOGS WITH TWO STRAINS OF THE VIRUS AND SEROLOGICAL INVESTIGATIONS WITH THE COMPLEMENT-FIXATION TEST

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Please use this identifier to cite or link to this item:https://doi.org/10.14943/jjvr.5.1.27

Title: STUDIES ON HEPATITIS CONTAGIOSA CANIS I. : INFECTION EXPERIMENTS ON DOGS WITH TWO STRAINS OF THE VIRUS AND SEROLOGICAL INVESTIGATIONS WITH THE COMPLEMENT-FIXATION TEST
Authors: OSAMURA, Kazuo Browse this author
HIRATO, Katsushichi Browse this author
SHIMIZU, Kiheiji Browse this author
SOEKAWA, Masao Browse this author
Issue Date: 25-Mar-1957
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 5
Issue: 1
Start Page: 27
End Page: 38
Abstract: 1. By using two strains, "YAMAGUCHI" and "MATSUDA", of H.c.c. which were encountered in Sapporo, serial transmission experiments on puppies aged 14〜90 days were conducted. In case of the "MATSUDA" strain, the fatal infection could be transferred to the 3rd passage, however only non-fatal infection occurred in dogs at the 4th passage. On the other hand, in the "YAMAGUCHI" strain the authors could not bring out any fatal infections. 2. The clinical symptoms of puppies were variable even within the same litter. Fatal infection was found to occur in 28.6% (8/28) in the "MATSUDA" strain but 0% in the "YAMAGUCHI" strain. The total infection rates including fatal, severe, mild or inapparent form were 75% (21/28) with the former and 60% (6/10) with the latter strain. 3. Complement-fixing antibody was developed during the period of 12〜15 days after inoculation. There seems to be no relationship among route, dose, severity of the clinical signs or viral strains examined. 4. In order to ascertain the prevalence of this disease in Japan, a survey on distribution of C.F. antibody among dogs from 4 districts was conducted. One hundred and eighty-six dog serum samples out of 374,nearly 50%, reacted positively. There seems not to be very much difference among districts (44〜57%).
Type: bulletin (article)
URI: http://hdl.handle.net/2115/1704
Appears in Collections:Japanese Journal of Veterinary Research > Volume 5, Number 1

Submitter: 獣医学部図書室

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