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Formation of GABAergic synapses in the cerebellum

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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/17159

Title: Formation of GABAergic synapses in the cerebellum
Authors: Takayama, Chitoshi Browse this author →KAKEN DB
Keywords: Glutamic acid decarboxylase
GABA receptor
GABA transporter
reeler mutant mouse
Issue Date: Sep-2005
Publisher: Taylor & Francis
Journal Title: The Cerebellum
Volume: 4
Issue: 3
Start Page: 171
End Page: 177
Publisher DOI: 10.1080/14734220510008012
PMID: 16147949
Abstract: In the adult central nervous system (CNS), γ‐amino butyric acid (GABA) is a predominant inhibitory neurotransmitter, and is involved in the expression of various higher brain functions. In the cerebellum, formation of GABAergic synapses is crucial for cerebellar functions. However, it is not fully understood how GABAergic synapses and networks are formed. We are morphologically investigating the developmental changes in GABAergic signaling and the mechanisms underlying the assembly of GABAergic synapses using the cerebellum, which provides an ideal system for the investigation of brain development. The anatomy and development of GABAergic synapses and networks in the cerebellar cortex are reviewed, the key factors for the formation of GABAergic synapses are addressed, and the mechanisms underlying the formation of cerebellar GABAergic networks are discussed.
Relation: http://www.taylorandfrancisgroup.com/
Type: article (author version)
URI: http://hdl.handle.net/2115/17159
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 高山 千利

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