HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine >
Japanese Journal of Veterinary Research >
Volume 14, Number 3-4 >

NEUTRALIZATION OF TOXOPLASMS WITH SPECIAL REFERENCE TO THEIR INTRA- AND EXTRACELLULAR LOCALIZATION

Files in This Item:
KJ00003418297.pdf1.48 MBPDFView/Open
Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.14.3-4.91

Title: NEUTRALIZATION OF TOXOPLASMS WITH SPECIAL REFERENCE TO THEIR INTRA- AND EXTRACELLULAR LOCALIZATION
Authors: IWASAKI, Naoko Browse this author
YANAGAWA, Ryo Browse this author
Issue Date: Dec-1966
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 14
Issue: 3-4
Start Page: 91
End Page: 102
Abstract: Neutralization in vitro of toxoplasms was investigated paying special attention to their intra- and extracellular localization. Toxoplasms were obtained from the ascites of infected mice. To detect the neutralization effect, mice were used as experimental animals, the subcutaneous route of inoculation proved to be successful. Inactivated immune rabbit serum neutralized extracellular, but not intracellular toxoplasms. Addition of fresh human serum to the neutralization system decreased the number of intracellular toxoplasms resulting in a considerable acceleration of neutralizing effect. This finding was investigated and the authors found that this was due to the cytolytic action of human serum on mouse ascitic cells containing toxoplasma intracellularly. The lysis of mouse ascitic cells by human serum was proved by microscopic examinations and also by demonstrating the loss of cell nucleotide. It is to be emphasized that toxoplasms could be neutralized by heat stable specific antibody, in accordance with the previous report of YANAGAWA & HIRATO (1963).
Type: bulletin (article)
URI: http://hdl.handle.net/2115/1843
Appears in Collections:Japanese Journal of Veterinary Research > Volume 14, Number 3-4

Submitter: 獣医学部図書室

Export metadata:

OAI-PMH ( junii2 , jpcoar )

MathJax is now OFF:


 

Feedback - Hokkaido University