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Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia.
| Title: | Aleukemic leukemia cutis in a patient with Philadelphia chromosome-positive biphenotypic leukemia. |
| Authors: | Onozawa, Masahiro Browse this author | | Hashino, Satoshi Browse this author | | Kanamori, Hiroe Browse this author | | Izumiyama, Koh Browse this author | | Yonezumi, Masakatsu Browse this author | | Chiba, Koji Browse this author | | Kondo, Takeshi Browse this author | | Fukuhara, Takashi Browse this author | | Tanaka, Junji Browse this author | | Imamura, Masahiro Browse this author | | Asaka, Masahiro Browse this author |
| Keywords: | Aleukemic leukemia cutis | | Philadelphia chromosome | | Biphenotypic leukemia |
| Issue Date: | Oct-2004 |
| Publisher: | Carden Jennings Publishing Co., Ltd. |
| Journal Title: | International Journal of Hematology |
| Volume: | 80 |
| Issue: | 3 |
| Start Page: | 278 |
| End Page: | 280 |
| PMID: | 15540904 |
| Abstract: | Aleukemic leukemia cutis is a rare condition characterized by the invasion of leukemic blasts into the skin before their appearance in the peripheral blood. Leukemia cutis usually occurs in patients with myeloid leukemia, especially the myelomonocytic and monocytic types of acute myeloblastic leukemia. We describe the case of a 62-year-old woman with aleukemic leukemia cutis who developed Philadelphia-positive acute leukemia 1 month after skin involvement. Leukemic cells expressed both myeloid and B-cell lineage surface markers, and monoclonal rearrangement of the immunoglobulin heavy chain was detected by Southern blot analysis. This report is the first of a case of aleukemic leukemia cutis preceding Philadelphia-positive biphenotypic leukemia. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/18871 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 小野澤 真弘
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