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Volume 16, Number 4 >

ONCOGENICITY OF INFECTIOUS CANINE HEPATITIS VIRUS IN HAMSTERS

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この文献には次のDOIがあります:http://doi.org/10.14943/jjvr.16.4.145

タイトル: ONCOGENICITY OF INFECTIOUS CANINE HEPATITIS VIRUS IN HAMSTERS
著者: KINJO, Toshio 著作を一覧する
YANAGAWA, Ryo 著作を一覧する
FUJIMOTO, Yutaka 著作を一覧する
発行日: 1968年12月
出版者: The Graduate School of Veterinary Medicine
誌名: Japanese Journal of Veterinary Research
巻: 16
号: 4
開始ページ: 145
終了ページ: 158
抄録: Two out of the four strains of infectious canine hepatitis (ICH) virus were proved to be oncogenic for newborn hamsters. When newborn hamsters were inoculated subcutaneously, with strain FD of ICH virus, tumors developed at the site of inoculation in 3 of 21 hamsters, within 153 to 174 days of inoculation. But the subcutaneous tumors soon regressed and disappeared. Strain Woc-4 produced an intraperitoneal tumor in 1 out of 13 hamsters 198 days following an intraperitoneal inoculation. This tumor developed rapidly and became very large in size (6×6×4.5 cm) and weight (77 g). The intraperitoneal tumor was easily transplantable to hamsters. After the 2nd passage we got 100% positive takes and the latent period was shortened to less than a month. Both the primary and transplanted tumors were histologically diagnosed as an undifferentiated mesenchymal tumor. Attempts to recover the ICH virus from both the primary and transplanted tumors failed, but a complement fixing antibody to the tumor antigen and to the tissue culture T antigen of the ICH virus could be demonstrated in the sera of all tumor-bearing hamsters, tested.
資料タイプ: bulletin
URI: http://hdl.handle.net/2115/1916
出現コレクション:Volume 16, Number 4

 

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