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Japanese Journal of Veterinary Research >
Volume 28, Number 3 >

COMPARISON OF MEMBRANE IMMUNOFLUORESCENCE AND CYTOTOXICITY TESTS FOR DETECTION OF CELL SURFACE ANTIGENS OF MAREK'S DISEASE LYMPHOMA-DERIVED CELL LINE

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この文献には次のDOIがあります:http://doi.org/10.14943/jjvr.28.3.67

タイトル: COMPARISON OF MEMBRANE IMMUNOFLUORESCENCE AND CYTOTOXICITY TESTS FOR DETECTION OF CELL SURFACE ANTIGENS OF MAREK'S DISEASE LYMPHOMA-DERIVED CELL LINE
著者: SUZUKI, Kazuo 著作を一覧する
MIKAMI, Takeshi 著作を一覧する
KODAMA, Hiroshi 著作を一覧する
ONUMA, Misao 著作を一覧する
IZAWA, Hisao 著作を一覧する
発行日: 1980年10月 6日
出版者: The Graduate School of Veterinary Medicine
誌名: Japanese Journal of Veterinary Research
巻: 28
号: 3
開始ページ: 67
終了ページ: 74
抄録: The reactivity of an anti-MDCC-MSB 1 rabbit serum to Marek's disease tumor-associated surface antigen (MATSA) of a Marek's disease lymphomaderived cell line (MDCC-MSB 1) was compared by membrane immunofluorescence and cytotoxicity tests. Following results were obtained by both tests : 1) the similar reactivity of the antiserum in titrations, 2) the similar blocking activity patterns of the soluble antigens from MDCC-MSB 1 cells to the antiserum, and 3) the parallisms between the cytotoxic index and the frequency of positive cells for MATSA of the MDCC-MSB 1 cells treated with proteolytic enzymes. From these results, both tests appeared to be detecting a similar, if not identical, antigen. The cytotoxicity test was slightly more sensitive than the membrane immunofluorescence test.
資料タイプ: bulletin
URI: http://hdl.handle.net/2115/2198
出現コレクション:Volume 28, Number 3

 

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