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Volume 40, Number 4 >

DISSEMINATED INTRAVASCULAR COAGULATION (DIC) IN RABBIT HAEMORRHAGIC DISEASE

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この文献には次のDOIがあります:http://doi.org/10.14943/jjvr.40.4.133

タイトル: DISSEMINATED INTRAVASCULAR COAGULATION (DIC) IN RABBIT HAEMORRHAGIC DISEASE
著者: UEDA, Kaoru 著作を一覧する
PARK, Jae-Hak 著作を一覧する
OCHIAI, Kenji 著作を一覧する
ITAKURA, Chitoshi 著作を一覧する
キーワード: rabbit haemorrhagic disease
DIC
blood
hepatitis
calicivirus
発行日: 1992年12月28日
出版者: The Graduate School of Veterinary Medicine
誌名: Japanese Journal of Veterinary Research
巻: 40
号: 4
開始ページ: 133
終了ページ: 141
抄録: Seven rabbits experimentally infected with rabbit haemorrhagic disease virus were examined haematologically and histologically. Haematologically, activated partial thromboplastin time and prothrombin time were markedly prolonged in the terminal phase of the disease, just prior to death (all the animals died between 27 and 40 hr after inoculation with rabbit haemorrhagic disease virus). There was an increase in the titre of fibrin degradation products and a decrease in antithrombin III activity during the same interval. Acute necrotic hepatitis and disseminated intravascular coagulation (DIC) in many organs, including the lung, kidney, spleen and heart were the characteristic histopathological changes. Thus, the haematological and histological changes suggested that DIC was induced by rabbit haemorrhagic disease virus infection. Severe liver necrosis was considered to be a factor causing DIC by inducing a hypercoagulable condition in the systemic blood circulation.
資料タイプ: bulletin
URI: http://hdl.handle.net/2115/2404
出現コレクション:Volume 40, Number 4

 

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