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Volume 42, Number 2 >

A NEUTRAL SUGAR IS RESPONSIBLE FOR SEROVAR SPECIFICITY OF THE ANTIGENIC DETERMINANT OF LEPTOSPIRA INTERROGANS SEROVAR CANICOLA

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.42.2.103

Title: A NEUTRAL SUGAR IS RESPONSIBLE FOR SEROVAR SPECIFICITY OF THE ANTIGENIC DETERMINANT OF LEPTOSPIRA INTERROGANS SEROVAR CANICOLA
Authors: KASHIWASE, Hiroto Browse this author
ONO, Etsuro Browse this author
YANAGAWA, Ryo Browse this author
SHIMIZU, Yukio Browse this author
KIDA, Hiroshi Browse this author →KAKEN DB
Keywords: Leptospira
glycolipid
antigen
determinant
sugar
Issue Date: 31-Aug-1994
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 42
Issue: 2
Start Page: 103
End Page: 108
Abstract: To provide information on the chemical structures of antigenic determinants of leptospira, glycolipids of Leptospira interrogans serovar canicola strain Hond Utrecht IV (Ut-IV) and its antigenic variant selected in the presence of a serovar-specific monoclonal antibody were compared physicochemically. Gasliquid chromatography-mass spectrometry analysis revealed that the glycolipid of Ut-IV contained 6 neutral sugar species ; rhamnose, mannose, galactose, glucose, and unknown sugars III and IV, in addition to unknown sugars I and II that had been previously reported. On the other hand, the glycolipid of the variant lacked unknown sugar III, suggesting that this sugar is responsible for the serovar-specific antigenic determinant.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/2471
Appears in Collections:Japanese Journal of Veterinary Research > Volume 42, Number 2

Submitter: 獣医学部図書室

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