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Study on the usefulness of precise and simple dynamic balance tests for the evaluation of recovery from intravenous sedation with midazolam and propofol.

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Title: Study on the usefulness of precise and simple dynamic balance tests for the evaluation of recovery from intravenous sedation with midazolam and propofol.
Authors: Fujisawa, T. Browse this author →KAKEN DB
Takuma, S. Browse this author
Koseki, H. Browse this author
Kimura, K. Browse this author
Fukushima, K. Browse this author
Keywords: CONSCIOUS SEDATION
PROPOFOL
MIDAZOLAM
RECOVERY OF FUNCTION
MUSCULOSKELETAL EQUILIBRIUM
dynamic balance
computerized dynamic posturography
Issue Date: May-2007
Publisher: Cambridge University Press
Journal Title: European Journal of Anaesthesiology
Volume: 24
Issue: 5
Start Page: 425
End Page: 430
Publisher DOI: 10.1017/S0265021506001876
PMID: 17156507
Abstract: Background and objective: Dynamic balance involving movement of the centre of gravity is important for the evaluation of street fitness after sedation. The purpose of this study was to compare the recovery of dynamic balance after intravenous sedation with propofol or midazolam, and to investigate the usefulness of simple dynamic balance tests in evaluating the recovery. Methods: Fourteen young male volunteers underwent intravenous sedation with propofol and midazolam for 1 h each at an interval of more than 1 week. Computerized dynamic posturography using a multi-axial tilting platform, the 10-m maximum-speed walking test and the timed ‘up & go’ test (subjects stand up from a chair, walk 5 m and back with maximum speed and sit down again) were performed before and after sedation. The increase in each variable of the tests described above represents a reduction of function. Results: The score of the computerized dynamic posturography was significantly lower in propofol sedation than that in midazolam sedation until 40 min after the end of sedation (P = 0.006). The scores of maximum-speed walking test and timed ‘up & go’ test were significantly lower in propofol sedation than those in midazolam sedation till 60 min after the end of sedation, respectively (P = 0.035 and 0.042). The timed ‘up & go’ and maximum-speed walking tests were well and significantly correlated with computerized dynamic posturography in midazolam sedation (timed ‘up & go’ test vs. computerized dynamic posturography: r = 0.66, P < 0.01; and maximum-speed walking test vs. computerized dynamic posturography: r = 0.53, P < 0.01). Conclusion: The timed ‘up & go’ and maximum-speed walking tests are useful simple dynamic balance tests well correlated with precise computerized dynamic posturography for the evaluation of the recovery of dynamic balance from midazolam sedation in younger adults.
Rights: Copyright © 2007 Cambridge University Press. The paper has been accepted for publication and may appear in a revised form, subsequent to editorial input by Cambridge University Press, in the journal published by Cambridge University Press.
Relation: http://www.journals.cambridge.org/action/displayJournal?jid=EJA
Type: article (author version)
URI: http://hdl.handle.net/2115/25174
Appears in Collections:歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 藤澤 俊明

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