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Volume 44, Number 1 >

PARENTERAL STROBILAR DEVELOPMENT OF ECHINOCOCCUS MULTILOCULARIS IN SCID MICE

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.44.1.1

Title: PARENTERAL STROBILAR DEVELOPMENT OF ECHINOCOCCUS MULTILOCULARIS IN SCID MICE
Authors: INOHARA, Junko Browse this author
PLAYFORD, Matthew Charles Browse this author
NONAKA, Nariaki Browse this author
OOI, Hong-Kean Browse this author
OKU, Yuzaburo Browse this author
ITO, Mamoru Browse this author
KAMIYA, Masao Browse this author
Keywords: Echinococcus multilocularis
scid mice
strobilation
parenteral development
Issue Date: 31-May-1996
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 44
Issue: 1
Start Page: 1
End Page: 12
Abstract: Parenteral strobilation of Echinococcus multilocularis was observed in scid (severe combined immuno-deficient) mice after intracerebral, subcutaneous and intraperitoneal inoculation with protoscoleces. Evaginated protoscoleces and segmented worms were obtained at the inoculated sites. Most worms recovered from peritoneal cavity of scid mice were encapsulated by connective tissue and granulocytes but showed a maximum of 3 proglottids, elongation of genital primordia and vesiculation. Viability of worms recovered from the subcutaneous tissue and peritoneal cavity of scid mice were higher (69.1-91.4%) than those from the immunologically normal C.B-17 (4.0-48.0%) control mice. However, viabilities of worms from the cerebrum of both scid and C.B-17 were almost the same (87.7-94.4%). Worms recovered from scid mice showed further development of reproductive organs when transplanted into the small intestine of prednisolone treated golden hamster. These findings suggest that the parenteral milieu of scid mice allows adult development of E. multilocularis protoscoleces.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/2520
Appears in Collections:Japanese Journal of Veterinary Research > Volume 44, Number 1

Submitter: 獣医学部図書室

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