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Evaluation of coproantigen diagnosis for natural Echinococcus multilocularis infection in red foxes

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Title: Evaluation of coproantigen diagnosis for natural Echinococcus multilocularis infection in red foxes
Authors: MORISHIMA, Yasuyuki Browse this author
TSUKADA, Hideharu Browse this author
NONAKA, Nariaki Browse this author
OKU, Yuzaburo Browse this author
KAMIYA, Masao Browse this author
Keywords: oproantigen
Echinococcus multilocularis
Issue Date: 26-Feb-1999
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 46
Issue: 4
Start Page: 185
End Page: 189
Abstract: The validity of a coproantigen ELISA for Echinococcus multilocularis was evaluated by comparison of three diagnostic methods ; autopsy, egg examination and the ELISA. Of 71 foxes, 39 were found to be infected with the cestode at autopsy. The overall mean of worm burdens was 3,451, but the number varied (1-34,522). The ELISA could detect 94.9% (37/39) of the worm positives and there were no false-positives. Two false-negatives were infected with 1 and 4 cestodes, whereas 3 cases with similar worm burdens (2,4 and 6 worms) were diagnosed as positives. This indicates the detection limit of the assay may be equivalent to less than 10 (in the worm burden). On the other hand, egg examination showed low sensitivity (43.6%, 17/39). These results suggest the ELISA has a potential to replace for the conventional methods.
Type: bulletin (article)
Appears in Collections:Japanese Journal of Veterinary Research > Volume 46, Number 4

Submitter: 獣医学部図書室

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