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Duck influenza lacking evidence of disease signs and immune response

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タイトル: Duck influenza lacking evidence of disease signs and immune response
著者: Kida, H. 著作を一覧する
Yanagawa, R. 著作を一覧する
Matsuoka, Y. 著作を一覧する
発行日: 1980年11月
出版者: American Society for Microbiology
誌名: INFECTION AND IMMUNITY
巻: 30
号: 2
開始ページ: 547
終了ページ: 553
抄録: Influenza viruses A/duck/Hokkaido/5/77 (Hav7N2), A/budgerigar/Hokkaido/1/77 (Hav4Nav1), A/Kumamoto/22/76 (H3N2), A/Aichi/2/68 (H3N2), and A/New Jersey/8/76 (Hsw1N1) were experimentally inoculated into Pekin ducks. Of these, the influenza viruses of duck and budgerigar origin replicated in the intestinal tract of the ducks. The infected ducks shed the virus in the feces to high titers, but did not show clinical signs of disease and scarcely produced detectable serum antibodies. Using immunofluorescent staining, we demonstrated that the target cells of the duck virus in ducks were the simple columnar epithelial cells which form crypts in the large intestines, especially in the colon. After primary infection, the birds resisted reinfection with the duck virus at least for 28 days, but from 46 days onward they were susceptible to reinfection. These infections were quickly restricted by a brisk secondary immune response, reflected in the rapid appearance of high titers of antibody after reinoculation. In contrat to the avian influenza viruses, the remaining three influenza viruses of human origin did not replicate in the intestinal tract but did cause a serum antibody response.
Rights: Copyright © American Society for Microbiology
資料タイプ: article
URI: http://hdl.handle.net/2115/28075
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 喜田 宏

 

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