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Hokkaido University Collection of Scholarly and Academic Papers >
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Duck influenza lacking evidence of disease signs and immune response
| Title: | Duck influenza lacking evidence of disease signs and immune response |
| Authors: | Kida, H. Browse this author →KAKEN DB | | Yanagawa, R. Browse this author | | Matsuoka, Y. Browse this author |
| Issue Date: | Nov-1980 |
| Publisher: | American Society for Microbiology |
| Journal Title: | INFECTION AND IMMUNITY |
| Volume: | 30 |
| Issue: | 2 |
| Start Page: | 547 |
| End Page: | 553 |
| Publisher DOI: | 10.1128/iai.30.2.547-553.1980 |
| PMID: | 7439994 |
| Abstract: | Influenza viruses A/duck/Hokkaido/5/77 (Hav7N2), A/budgerigar/Hokkaido/1/77 (Hav4Nav1), A/Kumamoto/22/76 (H3N2), A/Aichi/2/68 (H3N2), and A/New Jersey/8/76 (Hsw1N1) were experimentally inoculated into Pekin ducks. Of these, the influenza viruses of duck and budgerigar origin replicated in the intestinal tract of the ducks. The infected ducks shed the virus in the feces to high titers, but did not show clinical signs of disease and scarcely produced detectable serum antibodies. Using immunofluorescent staining, we demonstrated that the target cells of the duck virus in ducks were the simple columnar epithelial cells which form crypts in the large intestines, especially in the colon. After primary infection, the birds resisted reinfection with the duck virus at least for 28 days, but from 46 days onward they were susceptible to reinfection. These infections were quickly restricted by a brisk secondary immune response, reflected in the rapid appearance of high titers of antibody after reinoculation. In contrat to the avian influenza viruses, the remaining three influenza viruses of human origin did not replicate in the intestinal tract but did cause a serum antibody response. |
| Rights: | Copyright © American Society for Microbiology |
| Type: | article |
| URI: | http://hdl.handle.net/2115/28075 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 喜田 宏
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