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Coagulation-fibrinolysis is more enhanced in twin than in singleton pregnancies

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タイトル: Coagulation-fibrinolysis is more enhanced in twin than in singleton pregnancies
著者: Morikawa, Mamoru 著作を一覧する
Yamada, Takashi 著作を一覧する
Turuga, Noriko 著作を一覧する
Cho, Kazutoshi 著作を一覧する
Yamada, Hideto 著作を一覧する
Sakuragi, Noriaki 著作を一覧する
Minakami, Hisanori 著作を一覧する
キーワード: antithrombin activity
発行日: 2006年10月
出版者: Walter de Gruyter
誌名: Journal of Perinatal Medicine
巻: 34
号: 5
開始ページ: 392
終了ページ: 397
出版社 DOI: 10.1515/JPM.2006.078
抄録: Aims: To examine whether coagulation-fibrinolysis in late pregnancy in women with twin pregnancies is more pronounced than in women with singleton pregnancies. Patients and methods: The plasma levels of D-dimer, fibrinogen/fibrin degradation products (FDP), and fibrinogen, the platelet count, and the antithrombin activity were assessed from 3 weeks before delivery until postpartum day 7 in 48 women (24 singleton and 24 twin pregnancies) without preeclampsia who underwent cesarean sections. Results: Women with singleton or twin pregnancies gave birth at 37.3±1.2 weeks or 35.2±1.4 weeks, respectively. Compared with singleton mothers, prenatal D-dimer and FDP levels were consistently and significantly higher among women with twin pregnancies. A significantly larger proportion of twin mothers exhibited prenatal levels of D-dimer >5.0 μg/mL, FDP >10.0 μg/mL, fibrinogen <420 mg/mL and antithrombin activity <70%. In addition, prenatal antithrombin activity in plasma was significantly lower. Conclusions: Coagulation-fibrinolysis is more enhanced in women with twin gestation than in women with singleton gestation.
資料タイプ: article (author version)
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 森川 守


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