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Volume 34, Number 3-4 >

ROLE OF ADHERENT MONONUCLEAR CELLS DERIVED FROM ADULT PIGS AND SUCKLING PIGLETS IN RESPONSE TO POKEWEED MITOGEN-INDUCED IMMUNOGLOBULIN PRODUCTION

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.34.3-4.279

Title: ROLE OF ADHERENT MONONUCLEAR CELLS DERIVED FROM ADULT PIGS AND SUCKLING PIGLETS IN RESPONSE TO POKEWEED MITOGEN-INDUCED IMMUNOGLOBULIN PRODUCTION
Authors: HAGIWARA, Shintaroh Browse this author
MAEDE, Yoshimitsu Browse this author →KAKEN DB
OHSUGI, Takeo Browse this author
NAMIOKA, Shigeo Browse this author
Keywords: Adherent mononuclear cells
immunoglobulin production
suckling piglet
pokeweed mitogen
Issue Date: 31-Oct-1986
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 34
Issue: 3-4
Start Page: 279
End Page: 289
Abstract: The effect of monocytes as an activator of a function of lymphocytes in pigs was studied using an in vitro Ig production system with pokeweed mitogen (PWM). When mononuclear cells (lymphocytes) from adult pigs were stimulated by PWM, optimal number of adherent cells (monocytes) collected from serum coated plastic Petri dishes were required for the generation of Ig producing cells, whereas the production was suppressed by the addition of excessive adherent cells. In neonatal and suckling piglets up to 6 weeks of age, PWM induced B lymphocyte differentiation was enhanced by addition of adherent cells from peripheral blood of adult pigs. On the other hand, adherent cells derived from piglets did not have the effect of increasing Ig production in the in vitro Ig production system with lymphocytes (non-adherent) derived from adult pigs.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/3024
Appears in Collections:Japanese Journal of Veterinary Research > Volume 34, Number 3-4

Submitter: 獣医学部図書室

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