|
Hokkaido University Collection of Scholarly and Academic Papers >
Hokkaido University Hospital >
Peer-reviewed Journal Articles, etc >
Epithelioid sarcoma presenting as pulmonary cysts with cancer antigen 125 expression
| Title: | Epithelioid sarcoma presenting as pulmonary cysts with cancer antigen 125 expression |
| Other Titles: | A Case of Pulmonary Metastasis of Epithelioid Sarcoma Presenting as Pulmonary Cysts with CA125 Expression |
| Authors: | KIKUCHI, Eiki Browse this author | | KINOSHITA, Ichiro Browse this author | | YAMAZAKI, Koichi Browse this author | | ITOH, Tomoo Browse this author | | SHIMIZU, Tadamichi Browse this author | | SHIMIZU, Hiroshi Browse this author →KAKEN DB | | NISHIMURA, Masaharu Browse this author |
| Keywords: | epithelioid sarcoma | | pulmonary metastasis | | pulmonary cyst | | pneumothorax | | immunohistochemistry | | CA125 |
| Issue Date: | Nov-2006 |
| Publisher: | Blackwell Publishing |
| Journal Title: | Respirology |
| Volume: | 11 |
| Issue: | 6 |
| Start Page: | 826 |
| End Page: | 829 |
| Publisher DOI: | 10.1111/j.1440-1843.2006.00925.x |
| PMID: | 17052316 |
| Abstract: | A 39-year-old Japanese woman presented with a swollen right hand and a right-sided pneumothorax. Chest CT revealed bilateral multiple pulmonary thin-walled cysts measuring ≤1 cm in diameter and small nodules. An initial skin biopsy led to a misdiagnosis of metastatic adenocarcinoma, as tumour cells were positive for cytokeratin, epithelial membrane antigen, carcinoembryonic antigen and cancer antigen 125. However, chemotherapy proved ineffective, and the skin biopsy was repeated. A final diagnosis of epithelioid sarcoma (ES) was made. Open lung biopsy showed that the pulmonary nodules represented metastases of ES. Although the pulmonary cyst walls did not contain tumour cells, bronchiolar wall adjacent to the cysts had been infiltrated by tumour cells. These findings suggested that pulmonary cysts, a rare form of pulmonary metastases from soft tissue sarcomas, had developed through a ball-valve effect of metastatic tumour in small airways. However, presence of cancer antigen 125 hindered obtaining a correct diagnosis of ES. |
| Rights: | The definitive version is available at www.blackwell-synergy.com |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/30276 |
| Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 菊地 英毅
|
