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Volume 35, Number 1 >

NONSPECIFIC CELL-MEDIATED CYTOTOXICITY OF PERIPHERAL BLOOD LYMPHOCYTES DERIVED FROM SUCKLING PIGLETS

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.35.1.41

Title: NONSPECIFIC CELL-MEDIATED CYTOTOXICITY OF PERIPHERAL BLOOD LYMPHOCYTES DERIVED FROM SUCKLING PIGLETS
Authors: ONIZUKA, Nobuyuki Browse this author
MAEDE, Yoshimitsu Browse this author →KAKEN DB
OHSUGI, Takeo Browse this author
NAMIOKA, Shigeo Browse this author
Keywords: nonspecific cell-mediated cytotoxicity
piglets
Issue Date: 30-Jan-1987
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 35
Issue: 1
Start Page: 41
End Page: 48
Abstract: Peripheral blood lymphocytes (PBL) from both adult pigs and suckling piglets showed natural killer (NK) activity against porcine B cell tumor cell line Mitsukaido, and this activity increased after incubation of PBL in glass Petri dishes at 37℃ for 16 h. The NK activity against homogeneous Mitsukaido was higher than that against heterogenous human chronic myelogenous leukemia cell line K562. NK activity of suckling piglets against Mitsukaido was not observed during 1 to 3 weeks of age. However, the activity rose slightly at 4 weeks old, and it remarkably at 5 weeks old. On the other hand, NK activity against K562 was not seen during 1 to 4 weeks of age, but at 5 weeks old, it was clearly recognized. These results indicated that the NK activity of piglets at 1 to 3 weeks of age was very low compared with adult controls.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/3029
Appears in Collections:Japanese Journal of Veterinary Research > Volume 35, Number 1

Submitter: 獣医学部図書室

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