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Protective Efficacy of Clinacanthus nutans on Yellow-head Disease in Black Tiger Shrimp (Penaeus monodon)

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Title: Protective Efficacy of Clinacanthus nutans on Yellow-head Disease in Black Tiger Shrimp (Penaeus monodon)
Authors: Direkbusarakom, S. Browse this author
Ruangpan, L. Browse this author
Ezura, Y. Browse this author
Yoshimizu, M. Browse this author →KAKEN DB
Keywords: herb
Clinacanthus nutans
antiviral substance
yellow-head disease
black tiger shrimp
Penaeus monodon
Issue Date: 20-Oct-1998
Publisher: 日本魚病学会
Journal Title: 魚病研究
Journal Title(alt): Fish pathology
Volume: 33
Issue: 4
Start Page: 401
End Page: 404
Abstract: The leaves of Clinacanthus nutans Lindua, a well-known Thai traditional medicine against viral disease in human being, were used to extract antiviral substances by ethanol using soxhlet apparatus. The extract was tested for its activity against yellow-head rhabdovirus (YRV) in black tiger shrimp (Penaeus monodon). Virucidal effect was investigated by observation of mortality of the shrimp injected with the extract-treated virus. The results showed that extract of C. nutans inhibited YRV in vitro with the minimum concentration of 1μg/ml. Protective efficacy of the extract on YRV infection in shrimp was tested by oral administration of the extract mixed pellet. As the result, the protective efficacies obtained were 44.6, 57.4 and 4.2% in the shrimp groups fed the extract at 0.1, 1 and 10g/kg pellet, respectively, indicating that the C. nutans extract mixed with pellet at 1 g/kg could most effectively control YRV infection in shrimp.
Type: article
Appears in Collections:水産科学院・水産科学研究院 (Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 吉水 守

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