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Glycosylseramides obtained from the starfish Asterias amurensis Lütken

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Title: Glycosylseramides obtained from the starfish Asterias amurensis Lütken
Authors: Shah, A.K.M. Azad Browse this author
Kinoshita, Mikio Browse this author
Kurihara, Hideyuki Browse this author →KAKEN DB
Ohnishi, Masao Browse this author
Takahashi, Koretaro Browse this author →KAKEN DB
Keywords: Asterias amurensis
sphingoid base
Issue Date: 2008
Publisher: Japan oil chemists' society
Journal Title: Journal of Oleo Science
Volume: 57
Issue: 9
Start Page: 477
End Page: 484
Abstract: Complex lipids in the starfish Asterias amurensis were characterized and the influence of sphingoid bases on human colon carcinoma Caco-2 cells was also investigated. Lipid content of gonad and viscera were 3.3% and 6.8%, respectively, in wet basis. The main lipid class in gonad was ceramide monohexoside (CMH) while triglyceride (TG) was predominant in the viscera. The most abundant fatty acid in the polar lipid was eicosapentaenoic acid (EPA, C20:5n-3), with the gonad and viscera samples having the highest proportion of 41.5% and 32.7%, respectively, of total fatty acids. Starfish internal organ contained enormous amount (0.7% in wet base) of glycosylceramide. Sphingoid bases of the glycosylceramide were mainly consisted of d22:2, d22:1 and d18:3. This sphingoid base exerted an apoptotic activity on Caco-2 cells. Thus, starfish could be used as a potential source of precious and useful complex lipids.
Type: article
Appears in Collections:水産科学院・水産科学研究院 (Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 高橋 是太郎

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