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Low prevalence of juvenile-onset Behçet's disease with uveitis in East/South Asian people
Title: | Low prevalence of juvenile-onset Behçet's disease with uveitis in East/South Asian people |
Authors: | Kitaichi, Nobuyoshi Browse this author →KAKEN DB | Miyazaki, Akiko Browse this author | Stanford, Miles R. Browse this author | Iwata, Daiju Browse this author →KAKEN DB | Chams, Hormoz Browse this author | Ohno, Shigeaki Browse this author →KAKEN DB |
Keywords: | Iris | Choroid | Public health | Inflammation | Epidemiology |
Issue Date: | Nov-2009 |
Publisher: | BMJ Publishing Group |
Journal Title: | British Journal of Ophthalmology |
Volume: | 93 |
Issue: | 11 |
Start Page: | 1428 |
End Page: | 1430 |
Publisher DOI: | 10.1136/bjo.2008.154476 |
PMID: | 19666928 |
Abstract: | Purpose: There is little information on the demographic and clinical characteristics of Behcet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres. Methods: Descriptive questionnaires were collected from 25 eye centers in 14 countries. The questionnaire surveyed details of juvenile-onset Behcet's disease with uveitis. Ethnic groups, clinical features, treatments, and prognosis of pediatric-age Behcet's disease were examined on a world scale. Results: The clinical data of 135 juvenile-onset and 1,227 adult-onset patients with uveitis were collected. The average age of disease diagnosis in the children was 11.7 years old. Of the ethnic groups identified: 54% were from Middle East, 43% from Europe, but only 2% from East/South Asian countries. By contrast, 19.2% of adult patients were from East or South Asia. The frequency of genital ulcers in juvenile patients was 38.7%, which was significantly lower than in adult cases (53.5%; p < 0.01). Conclusions: Behcet's disease with uveitis was less common in children than in adults in East/South Asia. Although the clinical features of the systemic disease were similar in children and adults, there was a lower frequency of genital ulceration in children. |
Description: | Asia-Pacific Intraocular Inflammation Study Group (APIISG) Excellent Contribution Young Investigator Award at 3rd Asia-Pacific Intraocular Inflammation (APII) Symposium (5-7 November 2009, Chongqing, China) | 第1回アジア太平洋内眼炎症学会最高貢献賞若手研究者賞受賞(国際ぶどう膜炎/アジア太平洋内眼炎合同シンポジウムにて、平成21年11月5日~7日、中国・重慶市) |
Rights: | This article has been accepted for publication in BJO following peer review. The definitive copyedited, typeset version Br J Ophthalmol 2009;93:1428-1430 is available online at : http://bjo.bmjjournals.com/ |
Relation: | http://bjo.bmjjournals.com/ |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/43032 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 北市 伸義
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