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Low prevalence of juvenile-onset Behçet's disease with uveitis in East/South Asian people

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Title: Low prevalence of juvenile-onset Behçet's disease with uveitis in East/South Asian people
Authors: Kitaichi, Nobuyoshi Browse this author
Miyazaki, Akiko Browse this author
Stanford, Miles R. Browse this author
Iwata, Daiju Browse this author
Chams, Hormoz Browse this author
Ohno, Shigeaki Browse this author
Keywords: Iris
Public health
Issue Date: Nov-2009
Publisher: BMJ Publishing Group
Journal Title: British Journal of Ophthalmology
Volume: 93
Issue: 11
Start Page: 1428
End Page: 1430
Publisher DOI: 10.1136/bjo.2008.154476
Abstract: Purpose: There is little information on the demographic and clinical characteristics of Behcet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres. Methods: Descriptive questionnaires were collected from 25 eye centers in 14 countries. The questionnaire surveyed details of juvenile-onset Behcet's disease with uveitis. Ethnic groups, clinical features, treatments, and prognosis of pediatric-age Behcet's disease were examined on a world scale. Results: The clinical data of 135 juvenile-onset and 1,227 adult-onset patients with uveitis were collected. The average age of disease diagnosis in the children was 11.7 years old. Of the ethnic groups identified: 54% were from Middle East, 43% from Europe, but only 2% from East/South Asian countries. By contrast, 19.2% of adult patients were from East or South Asia. The frequency of genital ulcers in juvenile patients was 38.7%, which was significantly lower than in adult cases (53.5%; p < 0.01). Conclusions: Behcet's disease with uveitis was less common in children than in adults in East/South Asia. Although the clinical features of the systemic disease were similar in children and adults, there was a lower frequency of genital ulceration in children.
Description: Asia-Pacific Intraocular Inflammation Study Group (APIISG) Excellent Contribution Young Investigator Award at 3rd Asia-Pacific Intraocular Inflammation (APII) Symposium (5-7 November 2009, Chongqing, China)
Rights: This article has been accepted for publication in BJO following peer review. The definitive copyedited, typeset version Br J Ophthalmol 2009;93:1428-1430 is available online at :
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Type: article (author version)
Appears in Collections:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 北市 伸義


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