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Low prevalence of juvenile-onset Behçet's disease with uveitis in East/South Asian people

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Title: Low prevalence of juvenile-onset Behçet's disease with uveitis in East/South Asian people
Authors: Kitaichi, Nobuyoshi Browse this author →KAKEN DB
Miyazaki, Akiko Browse this author
Stanford, Miles R. Browse this author
Iwata, Daiju Browse this author →KAKEN DB
Chams, Hormoz Browse this author
Ohno, Shigeaki Browse this author →KAKEN DB
Keywords: Iris
Public health
Issue Date: Nov-2009
Publisher: BMJ Publishing Group
Journal Title: British Journal of Ophthalmology
Volume: 93
Issue: 11
Start Page: 1428
End Page: 1430
Publisher DOI: 10.1136/bjo.2008.154476
PMID: 19666928
Abstract: Purpose: There is little information on the demographic and clinical characteristics of Behcet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres. Methods: Descriptive questionnaires were collected from 25 eye centers in 14 countries. The questionnaire surveyed details of juvenile-onset Behcet's disease with uveitis. Ethnic groups, clinical features, treatments, and prognosis of pediatric-age Behcet's disease were examined on a world scale. Results: The clinical data of 135 juvenile-onset and 1,227 adult-onset patients with uveitis were collected. The average age of disease diagnosis in the children was 11.7 years old. Of the ethnic groups identified: 54% were from Middle East, 43% from Europe, but only 2% from East/South Asian countries. By contrast, 19.2% of adult patients were from East or South Asia. The frequency of genital ulcers in juvenile patients was 38.7%, which was significantly lower than in adult cases (53.5%; p < 0.01). Conclusions: Behcet's disease with uveitis was less common in children than in adults in East/South Asia. Although the clinical features of the systemic disease were similar in children and adults, there was a lower frequency of genital ulceration in children.
Description: Asia-Pacific Intraocular Inflammation Study Group (APIISG) Excellent Contribution Young Investigator Award at 3rd Asia-Pacific Intraocular Inflammation (APII) Symposium (5-7 November 2009, Chongqing, China)
Rights: This article has been accepted for publication in BJO following peer review. The definitive copyedited, typeset version Br J Ophthalmol 2009;93:1428-1430 is available online at :
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 北市 伸義

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