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Volume 45, Number 2  >

Short-term hemodialysis treatment in dogs and cats with total uretic obstruction

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Title: Short-term hemodialysis treatment in dogs and cats with total uretic obstruction
Authors: MASHITA, Tadahisa Browse this author
YASUDA, Jun Browse this author
IIJIMA, Megumi Browse this author
TAKIGUCHI, Mitsuyoshi Browse this author
YAMAZAKI, Tadayoshi Browse this author
HASHIMOTO, Akira Browse this author
Keywords: Hemodialysis
Short dialysis
Blood flow
Issue Date: 29-Aug-1997
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 45
Issue: 2
Start Page: 59
End Page: 65
Abstract: This study evaluated the single-pass system for the short-term dialysis treatment of dogs and cats with experimental renal failure. The hemodialyzer was equipped with a thin and highly permeable Cuprophan membrane. Four animals (two dogs and two cats) with total uretic obstruction were dialyzed twice in a one-week period. The vascular access by venipuncture of external jugular vein delivered more than 5 ml/min/kg/body weight of blood repeatedly, even for the cats. The evaluation of the effects of the blood flow, dialysate flow and ultrafiltration pressure revealed that the blood flow was the most important factor for effective dialysis. A 300 ml/min dialysate flow provided enough clearance of blood urea nitrogen and creatinine. The ultrafiltration pressure played an important role in ensuring that the fluid removal was constant. Laboratory studies revealed a 50.0% (range 42.0 to 59.3%) reduction of blood urea nitrogen, a 48.7% (range 42.5 to 58.7%) reduction of creatinine, and a 49.8% (range 34.3 to 66.2%) reduction of inorganic phosphate during the dialysis treatment. No dialysis disequilibrium syndrome was shown by the clinical signs. We conclude that this short-term dialysis using a single-pass system for small animals was sufficiently applicable to dogs and cats, and that the optimal duration of the dialysis was 2 hours.
Type: bulletin (article)
Appears in Collections:Japanese Journal of Veterinary Research > Volume 45, Number 2

Submitter: 獣医学部図書室

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