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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Repeatability of Rest and Hyperemic Myocardial Blood Flow Measurements with 82Rb Dynamic PET
| Title: | Repeatability of Rest and Hyperemic Myocardial Blood Flow Measurements with 82Rb Dynamic PET |
| Authors: | Manabe, Osamu Browse this author | | Yoshinaga, Keiichiro Browse this author | | Katoh, Chietsugu Browse this author | | Naya, Masanao Browse this author | | deKemp, Robert A. Browse this author | | Tamaki, Nagara Browse this author →KAKEN DB |
| Keywords: | myocardial blood flow | | pharmacologic stress | | 82Rb |
| Issue Date: | 2009 |
| Publisher: | Society of Nuclear Medicine |
| Journal Title: | Journal of Nuclear Medicine |
| Volume: | 50 |
| Issue: | 1 |
| Start Page: | 68 |
| End Page: | 71 |
| Publisher DOI: | 10.2967/jnumed.108.055673 |
| PMID: | 19091892 |
| Abstract: | The repeatability of rest and hyperemic myocardial blood flow (MBF) measurements using 82Rb PET has not been evaluated. The aimof this study was to investigate the short-term repeatability of such measurements. Methods: Fifteen healthy volunteers underwent rest and pharmacologic stress 82Rb PET, repeated 60 min apart. Results: There was no significant difference in repeated rest MBF (0.77 6 0.25 vs. 0.82 6 0.25 mL/min/g, P 5 0.31; mean difference, 6.18% 6 12.22%) or repeated hyperemic MBF (3.35 6 1.37 vs. 3.39 6 1.37 mL/min/g, P 5 0.81; mean difference, 1.17% 6 13.64%). The repeatability coefficients were 0.19 mL/min/g for rest MBF and 0.92 mL/min/g for hyperemia. Conclusion:MBF using 82Rb is highly reproducible using a sameday short-term repeatability protocol. Serial MBF measurements with 82Rb PET should have the ability to quantify the acute effects of therapeutic interventions on MBF. |
| Rights: | Reprinted by permission of the Society of Nuclear Medicine |
| Type: | article |
| URI: | http://hdl.handle.net/2115/46752 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 玉木 長良
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