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Long-Term Survival in a Patient with Node-Positive Adult-Onset Xp11.2 Translocation Renal Cell Carcinoma

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Title: Long-Term Survival in a Patient with Node-Positive Adult-Onset Xp11.2 Translocation Renal Cell Carcinoma
Authors: Aoyagi, Toshiki Browse this author
Shinohara, Nobuo Browse this author
Kubota-Chikai, Kanako Browse this author
Kuroda, Naoto Browse this author
Nonomura, Katsuya Browse this author
Keywords: Xp11.2 translocation
Transcription factor E3
Renal cell carcinoma
Lymph node
Nephrectomy
Lymphadenectomy
Issue Date: Jun-2011
Publisher: Karger
Journal Title: Urologia Internationalis
Volume: 86
Issue: 4
Start Page: 487
End Page: 490
Publisher DOI: 10.1159/000323866
PMID: 21335945
Abstract: Adult-onset Xp11.2 translocation renal cell carcinoma is a rare malignancy that has an aggressive clinical course and poor prognosis. The reasons for this include the fact that most patients have an advanced clinical stage at diagnosis and also that there is a lack of effective systemic therapy. We herein present the case of a 32-year-old woman suffering from node-positive Xp11.2 translocation renal cell carcinoma, who has undergone radical nephrectomy with an extensive retroperitoneal lymph node dissection, followed by two times of surgical resection for recurrent nodal disease. The patient has experienced no recurrent disease 4.5 years after the last operation and remains free of disease. Surgical approach to recurrent disease, if the recurrent site can be judged to be limited, might be one of the feasible treatment options in patients with Xp11.2 translocation renal cell carcinoma.
Rights: Copyright © 2011 S. Karger AG, Basel
Type: article (author version)
URI: http://hdl.handle.net/2115/46828
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 篠原 信雄

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