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Long-Term Survival in a Patient with Node-Positive Adult-Onset Xp11.2 Translocation Renal Cell Carcinoma
Title: | Long-Term Survival in a Patient with Node-Positive Adult-Onset Xp11.2 Translocation Renal Cell Carcinoma |
Authors: | Aoyagi, Toshiki Browse this author | Shinohara, Nobuo Browse this author | Kubota-Chikai, Kanako Browse this author | Kuroda, Naoto Browse this author | Nonomura, Katsuya Browse this author |
Keywords: | Xp11.2 translocation | Transcription factor E3 | Renal cell carcinoma | Lymph node | Nephrectomy | Lymphadenectomy |
Issue Date: | Jun-2011 |
Publisher: | Karger |
Journal Title: | Urologia Internationalis |
Volume: | 86 |
Issue: | 4 |
Start Page: | 487 |
End Page: | 490 |
Publisher DOI: | 10.1159/000323866 |
PMID: | 21335945 |
Abstract: | Adult-onset Xp11.2 translocation renal cell carcinoma is a rare malignancy that has an aggressive clinical course and poor prognosis. The reasons for this include the fact that most patients have an advanced clinical stage at diagnosis and also that there is a lack of effective systemic therapy. We herein present the case of a 32-year-old woman suffering from node-positive Xp11.2 translocation renal cell carcinoma, who has undergone radical nephrectomy with an extensive retroperitoneal lymph node dissection, followed by two times of surgical resection for recurrent nodal disease. The patient has experienced no recurrent disease 4.5 years after the last operation and remains free of disease. Surgical approach to recurrent disease, if the recurrent site can be judged to be limited, might be one of the feasible treatment options in patients with Xp11.2 translocation renal cell carcinoma. |
Rights: | Copyright © 2011 S. Karger AG, Basel |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/46828 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 篠原 信雄
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