|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning
| Title: | A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning |
| Authors: | Sutherland, Kenneth Browse this author | | Miyajima, Satoshi Browse this author | | Date, Hiroyuki Browse this author | | Shirato, Hiroki Browse this author | | Ishikawa, Masayori Browse this author | | Murakami, Masao Browse this author | | Yamagiwa, Mitsuru Browse this author | | Bolton, Paul Browse this author | | Tajima, Toshiki Browse this author |
| Keywords: | proton therapy | | ocular melanoma | | Monte Carlo simulation | | laser acceleration |
| Issue Date: | Jan-2010 |
| Publisher: | Springer Japan |
| Journal Title: | Radiological Physics and Technology |
| Volume: | 3 |
| Issue: | 1 |
| Start Page: | 16 |
| End Page: | 22 |
| Publisher DOI: | 10.1007/s12194-009-0071-4 |
| PMID: | 20821097 |
| Abstract: | Results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot-scanning method utilizing active energy modulation which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil-beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread is suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators. |
| Rights: | The original final publication is available at www.springerlink.com |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/46897 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: Kenneth Sutherland
|
