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A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning

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Title: A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning
Authors: Sutherland, Kenneth Browse this author
Miyajima, Satoshi Browse this author
Date, Hiroyuki Browse this author
Shirato, Hiroki Browse this author
Ishikawa, Masayori Browse this author
Murakami, Masao Browse this author
Yamagiwa, Mitsuru Browse this author
Bolton, Paul Browse this author
Tajima, Toshiki Browse this author
Keywords: proton therapy
ocular melanoma
Monte Carlo simulation
laser acceleration
Issue Date: Jan-2010
Publisher: Springer Japan
Journal Title: Radiological Physics and Technology
Volume: 3
Issue: 1
Start Page: 16
End Page: 22
Publisher DOI: 10.1007/s12194-009-0071-4
PMID: 20821097
Abstract: Results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot-scanning method utilizing active energy modulation which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil-beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread is suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators.
Rights: The original final publication is available at www.springerlink.com
Type: article (author version)
URI: http://hdl.handle.net/2115/46897
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: Kenneth Sutherland

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