A potential glucuronate glycosyl donor with 2-O-acyl-6,3-lactone structure: efficient synthesis of glycosaminoglycan disaccharides


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Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/47554

Title:	A potential glucuronate glycosyl donor with 2-O-acyl-6,3-lactone structure: efficient synthesis of glycosaminoglycan disaccharides
Authors:	Furukawa, Takayuki Browse this author
	Hinou, Hiroshi Browse this author →KAKEN DB
	Shimawaki, Ken Browse this author
	Nishimura, Shin-Ichiro Browse this author
Keywords:	Glycosylation
	Lactones
	Carbohydrate
	Glycosaminoglycans
	1,2-trans Stereoselectivity
Issue Date:	26-Oct-2011
Publisher:	Elsevier
Journal Title:	Tetrahedron Letters
Volume:	52
Issue:	43
Start Page:	5567
End Page:	5570
Publisher DOI:	10.1016/j.tetlet.2011.08.024
Abstract:	Development of β-selective glucuronylation reaction using phenyl 2,4-di-O-acetyl-1-thio-β-D-glucopyranosidurono-6,3-lactone was described. Glycosylations of this glycosyl donor with hexosamine derivatives proceeded with excellent yield and β-stereoselectivity to afford glycosaminoglycan-type disaccharides.
Type:	article (author version)
URI:	http://hdl.handle.net/2115/47554
Appears in Collections:	生命科学院・先端生命科学研究院 (Graduate School of Life Science / Faculty of Advanced Life Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 比能洋

OAI-PMH ( junii2 , jpcoar )

- Hokkaido University