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Volume 59 Number 4 >

Basosquamous carcinoma with systemic metastasis in a miniature Pinscher

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Title: Basosquamous carcinoma with systemic metastasis in a miniature Pinscher
Authors: Shin, Sang-Kyung Browse this author
Kim, Tae-Wang Browse this author
Youm, So-Young Browse this author
Kim, Gonhyung Browse this author
Na, Ki-Jeong Browse this author
Chang, Dongwoo Browse this author
Ahn, Byeongwoo Browse this author
Keywords: basosquamous carcinoma
cytokeratin 34βE12
pancytokeratin AE1/AE3
Issue Date: Nov-2011
Publisher: Graduate School of Veterinary Medicine, Hokkaido University
Journal Title: Japanese Journal of Veterinary Research
Volume: 59
Issue: 4
Start Page: 173
End Page: 179
Abstract: Basosquamous carcinoma (BSCC) is a rare malignancy, primarily composed of basal cells with foci of squamous differentiation. It is considered to be histologically an intermediate type between basal cell carcinoma and squamous cell carcinoma, and is known to have aggressive behaviors. BSCC occurred in a 17-year-old female minipin with a history of surgical excision for a mammary tumor. The right upper hindlimb was severely enlarged to 8 × 5 cm. Cross-section showed a homogenous white to yellow-white mass compressing the surrounding muscular tissues. The tumor metastasized also to the lungs, heart, abdominal cavity, liver and salivary gland. Microscopically, basaloid cells were crowded into solid nests or lobules separated by well-developed fibrous tissues with occasional keratinizations. Since there was no skin lesions, the tumor is assumed to be originated from the formerly present tumor in mammary gland. To our literature review, this case is the first BSCC with systemic metastasis in a dog.
Type: bulletin (article)
Appears in Collections:Japanese Journal of Veterinary Research > Volume 59 Number 4

Submitter: 獣医学部図書室

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