Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Virtual bronchoscopic navigation combined with endobronchial ultrasound to diagnose small peripheral pulmonary lesions : a randomised trial
Title: | Virtual bronchoscopic navigation combined with endobronchial ultrasound to diagnose small peripheral pulmonary lesions : a randomised trial |
Authors: | Ishida, Takashi Browse this author | Asano, Fumihiro Browse this author | Yamazaki, Koichi Browse this author | Shinagawa, Naofumi Browse this author →KAKEN DB | Oizumi, Satoshi Browse this author →KAKEN DB | Moriya, Hiroshi Browse this author | Munakata, Mitsuru Browse this author | Nishimura, Masaharu Browse this author →KAKEN DB |
Issue Date: | Dec-2011 |
Publisher: | BMJ Publishing Group |
Journal Title: | Thorax |
Volume: | 66 |
Issue: | 12 |
Start Page: | 1072 |
End Page: | 1077 |
Publisher DOI: | 10.1136/thx.2010.145490 |
Abstract: | Background: Bronchoscopy using endobronchial ultrasound (EBUS) can help to diagnose small peripheral pulmonary lesions. However, although biopsy sites can be confirmed, a bronchoscope cannot be guided in EBUS. Virtual bronchoscopic navigation (VBN) can guide a bronchoscope with virtual images, but its value has not been confirmed. Methods: This prospective multicentre study examines the value of VBN-assisted EBUS for diagnosing small peripheral pulmonary lesions. 199 patients with small peripheral pulmonary lesions (diameter ≤ 30 mm) were randomly assigned to VBN-assisted (VBNA) or non-VBN-assisted (NVBNA) groups. A bronchoscope was introduced into the target bronchus of the VBNA group using the VBN system. Sites of specimen sampling were verified using EBUS with a guide sheath under fluoroscopy. Results: The diagnostic yield was higher for the VBNA than for the NVBNA group (80.4% vs 67.0%; p=0.032). The duration of the examination and time elapsed until the start of sample collection were reduced in the VBNA compared with the NVBNA group (median (range), 24.0 (8.7-47.0) vs 26.2 (11.6-58.6) min, p=0.016) and 8.1 (2.8-39.2) vs 9.8 (2.3-42.3) min, p=0.045, respectively). The only adverse event was mild pneumothorax in a patient from the NVBNA group. Conclusions: The diagnostic yield for small peripheral pulmonary lesions is increased when VBN is combined with EBUS. |
Type: | article |
URI: | http://hdl.handle.net/2115/47806 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 西村 正治
|