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Use of FDG PET to Evaluate Hyperbaric Oxygen Therapy for Bisphosphonate-Related Osteonecrosis of the Jaw

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Title: Use of FDG PET to Evaluate Hyperbaric Oxygen Therapy for Bisphosphonate-Related Osteonecrosis of the Jaw
Authors: Yamazaki, Yutaka Browse this author →KAKEN DB
Kitagawa, Yoshimasa Browse this author
Hata, Hironobu Browse this author
Abe, Takahiro Browse this author
Murai, Chika Browse this author
Shiga, Tohru Browse this author
Tamaki, Nagara Browse this author
Keywords: bisphosphonate-related osteonecrosis of the jaw
hyper baric oxygen therapy
Issue Date: Aug-2010
Publisher: Lippincott Williams & Wilkins
Journal Title: Clinical Nuclear Medicine
Volume: 35
Issue: 8
Start Page: 590
End Page: 591
Publisher DOI: 10.1097/RLU.0b013e3181e4df11
PMID: 20631506
Abstract: An 80-year-old man presented with painful swelling in the mandibular region and fistula with pus discharge that developed after tooth extractions. He had taken oral alendronate sodium hydrate and prednisolone for osteoporosis for five years. The lesion was diagnosed as bisphosphonate-related osteonecrosis of the jaw. FDG-PET revealed a high accumulation of FDG in the right mandibular region. The patient underwent hyperbaric oxygen therapy twenty times. FDG-PET SUVmax drastically decreased from 5.6 to 1.8 after hyper baric oxygen therapy, paralleling the change in clinical symptoms, while other modalities did not show remarkable changes. This is the first study demonstrating the utility of FDG-PET in monitoring hyper baric oxygen therapy for bisphosphonate-related osteonecrosis of the jaw.
Rights: This is a non-final version of an article published in final form in Clinical Nuclear Medicine 35(8), August 2010, pp 590-591
Type: article (author version)
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 山崎 裕

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