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Use of FDG PET to Evaluate Hyperbaric Oxygen Therapy for Bisphosphonate-Related Osteonecrosis of the Jaw
Title: | Use of FDG PET to Evaluate Hyperbaric Oxygen Therapy for Bisphosphonate-Related Osteonecrosis of the Jaw |
Authors: | Yamazaki, Yutaka Browse this author →KAKEN DB | Kitagawa, Yoshimasa Browse this author | Hata, Hironobu Browse this author | Abe, Takahiro Browse this author | Murai, Chika Browse this author | Shiga, Tohru Browse this author | Tamaki, Nagara Browse this author |
Keywords: | bisphosphonate-related osteonecrosis of the jaw | FDG-PET | hyper baric oxygen therapy |
Issue Date: | Aug-2010 |
Publisher: | Lippincott Williams & Wilkins |
Journal Title: | Clinical Nuclear Medicine |
Volume: | 35 |
Issue: | 8 |
Start Page: | 590 |
End Page: | 591 |
Publisher DOI: | 10.1097/RLU.0b013e3181e4df11 |
PMID: | 20631506 |
Abstract: | An 80-year-old man presented with painful swelling in the mandibular region and fistula with pus discharge that developed after tooth extractions. He had taken oral alendronate sodium hydrate and prednisolone for osteoporosis for five years. The lesion was diagnosed as bisphosphonate-related osteonecrosis of the jaw. FDG-PET revealed a high accumulation of FDG in the right mandibular region. The patient underwent hyperbaric oxygen therapy twenty times. FDG-PET SUVmax drastically decreased from 5.6 to 1.8 after hyper baric oxygen therapy, paralleling the change in clinical symptoms, while other modalities did not show remarkable changes. This is the first study demonstrating the utility of FDG-PET in monitoring hyper baric oxygen therapy for bisphosphonate-related osteonecrosis of the jaw. |
Rights: | This is a non-final version of an article published in final form in Clinical Nuclear Medicine 35(8), August 2010, pp 590-591 |
Relation: | http://journals.lww.com/nuclearmed/pages/default.aspx |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/47876 |
Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 山崎 裕
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