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Peer-reviewed Journal Articles, etc >
Heredity in Multiple System Atrophy
| Title: | Heredity in Multiple System Atrophy |
| Authors: | Soma, Hiroyuki Browse this author | | Yabe, Ichiro2 Browse this author →KAKEN DB | | Takei, Asako Browse this author | | Fujiki, Naoto Browse this author | | Yanagihara, Tetsuro Browse this author | | Sasaki, Hidenao Browse this author →KAKEN DB |
| Authors(alt): | 矢部, 一郎2 |
| Keywords: | Multiple System Atrophy | | Family History | | Multigenic Aetiology | | Spinocerebellar Ataxia | | Parkinsonism | | Neurodegenerative Disorders |
| Issue Date: | 15-Jan-2006 |
| Publisher: | Elsevier B.V. |
| Journal Title: | Journal of the Neurological Sciences |
| Volume: | 240 |
| Issue: | 1-2 |
| Start Page: | 107 |
| End Page: | 110 |
| Publisher DOI: | 10.1016/j.jns.2005.09.003 |
| PMID: | 16307759 |
| Abstract: | We investigated the family histories of 157 Japanese patients with probable or possible multiple system atrophy (MSA). A family history of neurodegenerative disorders was only detected in three MSA patients (1.9%). We evaluated these patients by careful neurological examination, neuroimaging studies, and genetic studies to exclude hereditary spinocerebellar ataxia with a similar clinical phenotype to MSA. The results indicated that one of them had a family history of MSA. Although the familial presence of neurodegenerative disorders is rare in MSA patients, the existence of such cases suggests that MSA may have a genetic background. |
| Relation: | http://www.sciencedirect.com/science/journal/0022510X |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/4859 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 矢部 一郎
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