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Modification of near-infrared cyanine dyes by serum albumin protein
| Title: | Modification of near-infrared cyanine dyes by serum albumin protein |
| Authors: | Awasthi, Kamlesh Browse this author | | Nishimura, Goro Browse this author →KAKEN DB |
| Issue Date: | Apr-2011 |
| Publisher: | Royal Society of Chemistry |
| Journal Title: | Photochemical & Photobiological Sciences |
| Volume: | 10 |
| Issue: | 4 |
| Start Page: | 461 |
| End Page: | 463 |
| Publisher DOI: | 10.1039/c0pp00271b |
| PMID: | 21152615 |
| Abstract: | Time-dependent nature of the complexes of IR806 dye and other similar near-infrared cyanine dyes in human serum albumin (HSA) have been studied by employing absorption, emission and time-correlated single photon counting techniques. The complex formation of IR806 with HSA modifies the native structure of IR806, results time dependent changes in the optical properties. The modification process of the dye and its complex formation with HSA is very slow and this takes about 90 min. The process of the formation of new complex is irreversible and totally controlled by the initial complex of IR806 and HSA. As far as we know, the new properties of cyanine dye have not been reported. These properties are very important for the near-infrared fluorescence imaging. |
| Rights: | Photochem. Photobiol. Sci., 2011, 10, 461-463 – Reproduced by permission of The Royal Society of Chemistry (RSC) for the European Society for Photobiology, the European Photochemistry Association, and the RSC |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/48721 |
| Appears in Collections: | 電子科学研究所 (Research Institute for Electronic Science) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 西村 吾朗
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