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Antibacterial Activity against Cariogenic Bacteria and Inhibition of Insoluble Glucan Production by Free Fatty Acids Obtained from Dried Gloiopeltis furcata

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Title: Antibacterial Activity against Cariogenic Bacteria and Inhibition of Insoluble Glucan Production by Free Fatty Acids Obtained from Dried Gloiopeltis furcata
Authors: Kurihara, Hideyuki Browse this author →KAKEN DB
Goto, Yurie Browse this author
Aida, Masahiko Browse this author
Hosokawa, Masashi Browse this author →KAKEN DB
Takahashi, Koretaro Browse this author →KAKEN DB
Keywords: Gloiopeltis furcata
mutans streptococci
antibacterial activity
glucosyltransferase
inhibition
free fatty acid
Issue Date: 1999
Publisher: Japanese Society of Fisheries Science
Journal Title: Fisheries Science
Volume: 65
Issue: 1
Start Page: 129
End Page: 132
Publisher DOI: 10.2331/fishsci.65.129
Abstract: Antibacterial substance for mutans streptococci was obtained from dried Gloiopeltis furcata by chromatographic separation. The substance was determined to be a mixture of free fatty acids (FFAs), from the results of instrumental analyses. The FFAs obtained showed moderate antibacterial activity against mutans streptococci, with minimal inhibitory concentration values between 25 and 50μg/ml. These FFAs also inhibited insoluble glucan production catalyzed by glucosyltransferase of Streptococcus sobrinus. Experiments carried out by using commercially available fatty acids indicated that unsaturated fatty acids showed more potent inhibition against insoluble glucan production than saturated fatty acids.
Rights: © 1999 公益社団法人日本水産学会
© 1999 The Japanese Society of Fisheries Science
Type: article
URI: http://hdl.handle.net/2115/48989
Appears in Collections:水産科学院・水産科学研究院 (Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 高橋 是太郎

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