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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Dental Medicine / Faculty of Dental Medicine >
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Carbon nanotube-coated silicone as a flexible and electrically conductive biomedical material
| Title: | Carbon nanotube-coated silicone as a flexible and electrically conductive biomedical material |
| Authors: | Matsuoka, Makoto Browse this author | | Akasaka, Tsukasa Browse this author →KAKEN DB | | Totsuka, Yasunori Browse this author →KAKEN DB | | Watari, Fumio Browse this author →KAKEN DB |
| Keywords: | Carbon nanotubes | | Silicone | | Scaffold | | Electro conductive | | Dielectrophoresis (DEP) |
| Issue Date: | 1-Apr-2012 |
| Publisher: | Elsevier B.V. |
| Journal Title: | Materials Science and Engineering: C |
| Volume: | 32 |
| Issue: | 3 |
| Start Page: | 574 |
| End Page: | 580 |
| Publisher DOI: | 10.1016/j.msec.2011.12.011 |
| Abstract: | Artificial cell scaffolds that support cell adhesion, growth, and organization need to be fabricated for various purposes. Recently, there have been increasing reports of cell patterning using electrical fields. We fabricated scaffolds consisting of silicone sheets coated with single-walled (SW) or multi-walled (MW) carbon nanotubes (CNTs) and evaluated their electrical properties and biocompatibility. We also performed cell alignment with dielectrophoresis using CNT-coated sheets as electrodes. Silicone coated with 10 μg/cm2 SWCNTs exhibited the least sheet resistance (0.8 kΩ/sq); its conductivity was maintained even after 100 stretching cycles. CNT coating also improved cell adhesion and proliferation. When an electric field was applied to the cell suspension introduced on the CNT-coated scaffold, the cells became aligned in a pearl-chain pattern. These results indicate that CNT coating not only provides electro-conductivity but also promotes cell adhesion to the silicone scaffold: cells seeded on the scaffold can be organized using electricity. These findings demonstrate that CNT-coated silicone can be useful as a biocompatible scaffold. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/49007 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 松岡 真琴
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