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Prospective Risk of Intrauterine Fetal Death in Monoamniotic Twin Pregnancies

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Title: Prospective Risk of Intrauterine Fetal Death in Monoamniotic Twin Pregnancies
Authors: Morikawa, Mamoru Browse this author →KAKEN DB
Yamada, Takashi Browse this author →KAKEN DB
Yamada, Takahiro Browse this author →KAKEN DB
Sato, Shoji Browse this author
Minakami, Hisanori Browse this author →KAKEN DB
Keywords: monoamnionicity
preterm birth
prospective risk
Issue Date: Aug-2012
Publisher: Cambridge University Press
Journal Title: Twin Research and Human Genetics
Volume: 15
Issue: 4
Start Page: 522
End Page: 526
Publisher DOI: 10.1017/thg.2012.30
PMID: 22853819
Abstract: This study was conducted to review the overall short-term outcome of monoamniotic twins in Japan and to determine the prospective risk of fetal death so as to adequately counsel parents with monoamniotic twins. Study subjects were 101 women with monoamniotic twins who were registered with the Japan Society of Obstetrics and Gynecology Successive Pregnancy Birth Registry System and who had given birth at ≥ 22 weeks of gestation during the past 8 years between 2002 and 2009. The gestational week at delivery (mean ± SD) was 31.8 ± 3.7. Fourteen women experienced intrauterine fetal death (IUFD). Short-term outcomes of co-twins born to the 14 women included 8 IUFDs, 1 early neonatal death within 7 days of life (END), and 5 survivors. Other four women experienced 5 ENDs. Thus, 13.9% (28/202) of infants died perinatally (22 IUFDs and 6 ENDs), 13.9% (14/101) of women experienced IUFD, and 82.2% (83/101) of women experienced neither IUFD nor END. Structural anomalies and twin-to-twin transfusion syndrome explained 17.9% (5 infants) and 10.7% (3 infants) of the 28 perinatal deaths, respectively. The prospective risk of intrauterine fetal death was 13.9% (14/101) for women who reached gestational week 22^[-0/7], gradually decreasing thereafter but remaining at between 4.5% and 8.0% between gestational week 30^[-0/7] and 36^[-0/7].
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 森川 守

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