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Chronological Change in Pulmonary Vascular Response to Hypoxia in Hepatopulmonary Syndrome

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Title: Chronological Change in Pulmonary Vascular Response to Hypoxia in Hepatopulmonary Syndrome
Authors: Tanino, Yoshinori Browse this author
Makita, Hironi Browse this author
Tsujino, Ichizo Browse this author →KAKEN DB
Shinano, Hideki Browse this author
Nishimura, Masaharu Browse this author →KAKEN DB
Keywords: Hepatopulmonary syndrome
Spontaneous resolution
Pulmonary hypertension
Pulmonary vascular response
Issue Date: Aug-2012
Publisher: Karger
Journal Title: Respiration
Volume: 84
Issue: 3
Start Page: 242
End Page: 245
Publisher DOI: 10.1159/000336622
PMID: 22456488
Abstract: We here present a case with hepatopulmonary syndrome (HPS) where spontaneous resolution of severe hypoxaemia occurred with the development of pulmonary hypertension over several years after the initial diagnosis of HPS. The pulmonary vascular responses to hypoxia examined before and after the spontaneous resolution of HPS confirmed that the pathogenesis of HPS could be functional and reversible in nature. To the best of our knowledge, this is the first report demonstrating a remarkable change in the pulmonary vascular response to hypoxia before and after the spontaneous resolution of hypoxaemia in HPS.
Rights: Copyright © 2012 S. Karger AG, Basel
Type: article (author version)
URI: http://hdl.handle.net/2115/50398
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 西村 正治

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