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11C-Methionine positron emission tomography may monitor the activity of encephalitis
| Title: | 11C-Methionine positron emission tomography may monitor the activity of encephalitis |
| Authors: | Hirata, Kenji Browse this author →KAKEN DB | | Shiga, Tohru Browse this author →KAKEN DB | | Fujima, Noriyuki Browse this author | | Manabe, Osamu Browse this author | | Usui, Reiko Browse this author | | Kuge, Yuji Browse this author →KAKEN DB | | Tamaki, Nagara Browse this author →KAKEN DB |
| Keywords: | Encephalitis | | positron emission tomography | | methionine | | therapy monitoring |
| Issue Date: | Dec-2012 |
| Publisher: | Royal Society of Medicine Press |
| Journal Title: | Acta Radiologica |
| Volume: | 53 |
| Issue: | 10 |
| Start Page: | 1155 |
| End Page: | 1157 |
| Publisher DOI: | 10.1258/ar.2012.120382 |
| PMID: | 22993272 |
| Abstract: | Encephalitis is generally diagnosed by clinical symptoms, cerebrospinal fluid examination, and imaging studies including CT, MR imaging and perfusion single photon emission tomography (SPECT). However, the role of positron emission tomography (PET) in diagnosis of encephalitis remains unclear. A 49-year-old woman presenting with coma and elevated inflammatory reaction was diagnosed as having encephalitis according to slow activity on electroencephalogram, broad cortical lesion in MR fluid attenuated inversion recovery image, and increased blood flow demonstrated by SPECT. PET revealed increased accumulation of 11C-methionine (MET) in the affected brain tissues. After the symptom had improved two months later, the accumulation of MET as well as the abnormal findings of MR imaging and SPECT was normalized. This case indicated that MET PET may monitor the activity of encephalitis. |
| Rights: | Acta Radiol, December 2012, 53(10), pp.1155-1157, doi: 10.1258/ar.2012.120382. This is the final draft, after peer-review, of a manuscript published in Acta Radiologica. The definitive version, detailed above, is available online at www.rsmjournals.com. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/52053 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 平田 健司
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