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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine >
Peer-reviewed Journal Articles, etc >
Borrelia miyamotoi Infections among Wild Rodents Show Age and Month Independence and Correlation with Ixodes persulcatus Larval Attachment in Hokkaido, Japan
| Title: | Borrelia miyamotoi Infections among Wild Rodents Show Age and Month Independence and Correlation with Ixodes persulcatus Larval Attachment in Hokkaido, Japan |
| Authors: | Taylor, Kyle R. Browse this author | | Takano, Ai Browse this author | | Konnai, Satoru Browse this author →KAKEN DB | | Shimozuru, Michito Browse this author | | Kawabata, Hiroki Browse this author | | Tsubota, Toshio Browse this author →KAKEN DB |
| Keywords: | Borrelia | | vectors | | Lyme disease | | ticks | | Ixodes persulcatus | | relapsing fever |
| Issue Date: | Feb-2013 |
| Publisher: | Mary Ann Liebert |
| Journal Title: | Vector-Borne and Zoonotic Diseases |
| Volume: | 13 |
| Issue: | 2 |
| Start Page: | 92 |
| End Page: | 97 |
| Publisher DOI: | 10.1089/vbz.2012.1027 |
| PMID: | 23210636 |
| Abstract: | To clarify how Borrelia miyamotoi is maintained in the environment in Hokkaido, we examined Ixodes persulcatus for its prevalence among wild rodents and its tick vector by detecting a portion of the borrelial flaB gene in rodent urinary bladder and blood samples, and from whole ticks. We compared B. miyamotoi infection rates to Borrelia garinii and Borrelia afzelii, which are human Lyme disease pathogens also carried by wild rodents, and which are transmitted by the same vector tick. Whereas B. garinii and B. afzelii showed age dependence of infection rates among wild rodents (18.4% and 9.9% among adults and 6.0% and 3.4% among sub-adults, respectively) when looking at urinary bladder samples, B. miyamotoi infection rates were not age dependent for either blood (4.2% among adults, and 7.9% among sub-adults) or urinary bladder samples (1.0% among adults, and 1.7% among sub-adults). Moreover, while B. garinii and B. afzelii infection rates showed increases across months (June, July [p < 0.05] and August [p < 0.01] had higher rates than in May for adult rodents with B. garinii, and July and August had higher rates than in May [p < 0.01] for adult rodents with B. afzelii), B. miyamotoi infection rates did not show significant month dependence. These differences in month and age dependence led us to suspect that B. miyamotoi may not develop persistent infections in wild rodents, as B. garinii and B. afzelii are thought to. Furthermore, we examined the extent of rodent exposure to I. persulcatus nymphs and larvae throughout most of the tick's active season (May through September), and determined that B. miyamotoi infection rates in sub-adult rodents were correlated with larval burden (p < 0.01), suggesting that larvae may be very important in transmission of B. miyamotoi to wild rodents. |
| Rights: | This is a copy of an article published in the Vector-Borne and Zoonotic Diseases © 2013 copyright Mary Ann Liebert, Inc.; Vector-Borne and Zoonotic Diseases is available online at: http://online.liebertpub.com. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/52180 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 坪田 敏男
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