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A newly designed automatic pH-cycling system to simulate daily pH fluctuations.

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Title: A newly designed automatic pH-cycling system to simulate daily pH fluctuations.
Authors: Matsuda, Yasuhiro Browse this author →KAKEN DB
Komatsu, Hisanori Browse this author →KAKEN DB
Murata, Yukie Browse this author
Tanaka, Toru Browse this author →KAKEN DB
Sano, Hidehiko Browse this author →KAKEN DB
Keywords: Automatic pH-cycle
Demineralization and remineralization
Time-lapse analysis
Issue Date: Jun-2006
Publisher: Japanese Society for Dental Materials and Devices
Journal Title: Dental materials journal
Volume: 25
Issue: 2
Start Page: 280
End Page: 285
Publisher DOI: 10.4012/dmj.25.280
PMID: 16916230
Abstract: The aim of this study was to develop and evaluate an automatic pH-cycling system, which was intended for performing time-lapse analyses of dental caries. Two single-section specimens prepared from each of the five extracted human incisors were studied under a condition of 3- or 9-cycles/day for seven weeks. Increase of mineral loss (delta delta Z) and increase of Ld (delta Ld) were examined and compared at the end of every week during the study. In the 3-cycles/day condition, delta delta Z and delta Ld significantly increased only at Week 7. In the 9-cycles/day condition, delta deltaZ increased significantly from Week 5. delta Ld increased from Week 2, and then there were no further increases for the subsequent five weeks. Based on the results of this study, progression pattern was found to be significantly different between the two conditions. We therefore concluded that the automatic pH-cycling system which we have developed qualified as a model system that simulated the human oral cavity. As such, it could be beneficially employed to clarify the roles of many factors that cause or prevent caries development in human teeth.
Rights: Copyright © 2006 The Japanese Society for Dental Materials and Devices
Type: article
Appears in Collections:歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 松田 康裕

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