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Relation between alcohol consumption and arterial stiffness: A cross-sectional study of middle-aged Japanese women and men

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タイトル: Relation between alcohol consumption and arterial stiffness: A cross-sectional study of middle-aged Japanese women and men
著者: Sasaki, Sachiko 著作を一覧する
Yoshioka, Eiji 著作を一覧する
Saijo, Yasuaki 著作を一覧する
Kita, Toshiko 著作を一覧する
Okada, Eisaku 著作を一覧する
Tamakoshi, Akiko 著作を一覧する
Kishi, Reiko 著作を一覧する
キーワード: Alcohol consumption
Arterial stiffness
Brachial-ankle pulse wave velocity
Cardiovascular disease
Cardiovascular protection
発行日: 2013年12月
出版者: Elsevier science inc
誌名: Alcohol
巻: 47
号: 8
開始ページ: 643
終了ページ: 649
出版社 DOI: 10.1016/j.alcohol.2013.10.003
抄録: Epidemiological data indicate the existence of a J-shaped association between alcohol consumption and cardiovascular mobility and mortality. However, studies assessing the relationship between alcohol consumption and pulse wave velocity (PWV) as a marker of arterial stiffness have provided inconsistent results. In addition, data regarding the effect of alcohol on arterial stiffness in women has been limited. This study aimed to clarify the relationship between alcohol consumption and PWV among female and male workers in Japan. Study participants were local government employees in Hokkaido, Japan, who underwent annual health check-ups. All data were collected using self-administered questionnaires. The average daily alcohol consumption of the previous month, based on the alcohol concentration of each beverage type (g/day, ethanol equivalent), was estimated according to the frequency and amount of consumption. Data from 3893 participants (812 women and 3081 men) were analyzed. In women, non-drinkers had significantly higher PWV than women who consumed <10 g/day of alcohol. In men, compared with those who reportedly drank 20-39 g/day, non-drinkers and those who drank <20 g/day and >= 60 g/day had significantly higher PWV. Alcohol consumption showed a J-shaped association with PWV in men (p for quadratic term < 0.036) and marginally in women (p < 0.056). The results of stratified analyses by age groups showed a significant J-shaped association, which was most notable for men >45 years (p < 0.005). In middle-aged Japanese women and men, light-to-moderate alcohol consumption is associated with lower PWV, which in turn correlates with a reduction in vascular stiffness. (C) 2013 Elsevier Inc. All rights reserved.
資料タイプ: article (author version)
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 岸 玲子


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