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Diffuse infiltrating retinoblastoma invading subarachnoid space

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タイトル: Diffuse infiltrating retinoblastoma invading subarachnoid space
著者: Kase, Satoru 著作を一覧する
Yoshida, Kazuhiko 著作を一覧する
Suzuki, Shigenobu 著作を一覧する
Ohno, Shigeaki 著作を一覧する
Ishida, Susumu 著作を一覧する
キーワード: diffuse infiltrating retinoblastoma
subarachnoid space
optic nerve
発行日: 2011年 6月23日
出版者: Dove Medical Press
誌名: Clinical Ophthalmology
巻: 5
開始ページ: 861
終了ページ: 863
出版社 DOI: 10.2147/OPTH.S20913
抄録: We report herein an unusual case of diffuse infiltrating retinoblastoma involving the brain, which caused a patient’s death 27 months after enucleation. An eight-year-old boy complained of blurred vision in his right eye (OD) in October 2006. Funduscopic examination showed optic disc swelling, dense whitish vitreous opacity, and an orange-colored subretinal elevated lesion adjacent to the optic disc. Fluorescein angiography revealed hyperfluorescence in the peripapillary region at an early-phase OD. Because the size of the subretinal lesion and vitreous opacity gradually increased, he was referred to us. His visual acuity was 20/1000 OD on June 20, 2007. Slit-lamp biomicroscopy showed a dense anterior vitreous opacity. Ophthalmoscopically, the subretinal orange-colored area spread out until reaching the mid peripheral region. A B-mode sonogram and computed tomography showed a thick homogeneous lesion without calcification. Gadolinium-enhanced magnetic resonance imaging showed a markedly enhanced appearance of the underlying posterior retina. Enucleation of the right eye was performed nine months after the initial presentation. Histopathology demonstrated retinal detachment and a huge choroidal mass invading the optic nerve head. The tumor was consistent with diffuse infiltrating retinoblastoma. The patient died due to brain involvement 27 months after enucleation. Ophthalmologists should be aware that diffuse infiltrating retinoblastoma may show an unfavorable course if its diagnosis is delayed.
Relation (URI):
資料タイプ: article
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 石田 晋


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