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The effects of collagen hydrogel implantation in buccal dehiscence defects in beagles.

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2007 J Oral Tissue Engin 2007 5 87-95.pdf498.24 kBPDFView/Open
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Title: The effects of collagen hydrogel implantation in buccal dehiscence defects in beagles.
Authors: Miyaji, Hirofumi Browse this author →KAKEN DB
Sugaya, Tsutomu Browse this author →KAKEN DB
Kato, Katsuya Browse this author
Kawamura, Naoto Browse this author
Kawanami, Masamitsu Browse this author →KAKEN DB
Keywords: collagen hydrogel
periodontal regeneration
scafforld barrier
Issue Date: 30-Dec-2007
Publisher: 日本再生歯科医学会
Journal Title: Journal of oral tissue engineering
Volume: 5
Issue: 2
Start Page: 87
End Page: 95
Abstract: Type I collagen hydrogel treated by an ascorbate-copper ion crosslinking system is highly biocompatible and highly degradable in the body. The purpose of this study was to examine the effect of collagen hydrogel on periodontal wound healing in beagles. Sixty-four periodontal dehiscence type defects were created on the buccal roots of four beagles. Subsequently, collagen hydrogel was implanted in each defect in the experimental group and sutured, and, in the control group, the defect was sutured without any application of collagen hydrogel. The percentage of the length of new bone and new cementum in the experimental group was significantly greater than that in the control group at weeks 4 (p<0.01) and 8 (p<0.05). Significantly more junctional epithelium was observed in the control group than in the experimental group at weeks 2 (p<0.01) and 4 (p<0.05). These findings thus indicate that periodontal regeneration was stimulated by collagen hydrogel implantation in beagles.
Rights: 日本再生歯科医学会(利用は著作権の範囲内に限られます)
Type: article
Appears in Collections:歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 宮治 裕史

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