| Title: | Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy |
| Authors: | Sakashita, Tomohiro Browse this author →KAKEN DB |
| Homma, Akihiro Browse this author →KAKEN DB |
| Hatakeyama, Hiromitsu Browse this author →KAKEN DB |
| Kano, Satoshi Browse this author →KAKEN DB |
| Mizumachi, Takatsugu Browse this author |
| Furusawa, Jun Browse this author |
| Yoshida, Daisuke Browse this author |
| Fujima, Noriyuki Browse this author →KAKEN DB |
| Onimaru, Rikiya Browse this author →KAKEN DB |
| Tsuchiya, Kazuhiko Browse this author →KAKEN DB |
| Yasuda, Koichi Browse this author →KAKEN DB |
| Shirato, Hiroki Browse this author →KAKEN DB |
| Suzuki, Fumiyuki Browse this author |
| Fukuda, Satoshi Browse this author →KAKEN DB |
| Keywords: | Maxillary sinus cancer |
| Salvage surgery |
| Squamous cell carcinoma |
| Chemotherapy |
| Radiotherapy |
| Intra-arterial |
| Issue Date: | Apr-2014 |
| Publisher: | Elsevier |
| Journal Title: | The British journal of oral & maxillofacial surgery |
| Volume: | 52 |
| Issue: | 4 |
| Start Page: | 323 |
| End Page: | 328 |
| Publisher DOI: | 10.1016/j.bjoms.2014.01.018 |
| PMID: | 24582012 |
| Abstract: | Our aim was to evaluate the feasibility of salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy. We retrospectively analysed the records of 61 patients with cancer of the maxillary sinus who were treated in this way. Chemotherapy comprised 100-120 mg/m(2) superselective intra-arterial infusions of cisplatin given a median of 4 times weekly (range 2-5). Concurrent radiotherapy was given in a median dose of 65 Gy (range 24-70 Gy). Persistent or recurrent cancer of the maxillary sinus was found in 17 patients, of whom 11 had salvage surgery. The disease was controlled in 8 of the 11, and 7 of the 11 survived with no evidence of disease. Their 5-year overall survival was 61%. Two of the 11 developed serious operative complications. Salvage surgery for patients with persistent or recurrent cancer of the maxillary sinus treated by superselective chemoradiotherapy is both safe and successful. Salvage surgery is a good option when this sort of persistent or recurrent cancer is followed up after the regimen of chemoradiotherapy described. (C) 2014 Elsevier Inc. All rights reserved. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/57079 |
| Appears in Collections: | 国際連携研究教育局 : GI-CoRE (Global Institution for Collaborative Research and Education : GI-CoRE) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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