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Unusual clinical course of preeclampsia heralded by generalized edema
| Title: | Unusual clinical course of preeclampsia heralded by generalized edema |
| Authors: | Kojima, Takashi Browse this author | | Yamada, Takahiro Browse this author →KAKEN DB | | Yamada, Takashi Browse this author →KAKEN DB | | Morikawa, Mamoru Browse this author →KAKEN DB | | Cho, Kazutoshi Browse this author →KAKEN DB | | Minakami, Hisanori Browse this author →KAKEN DB |
| Keywords: | gestational edema | | preeclampsia | | thrombocytopenia | | vascular permeability |
| Issue Date: | Nov-2013 |
| Publisher: | Blackwell Publishing |
| Journal Title: | Journal of Obstetrics and Gynaecology Research |
| Volume: | 39 |
| Issue: | 11 |
| Start Page: | 1538 |
| End Page: | 1540 |
| Publisher DOI: | 10.1111/jog.12080 |
| PMID: | 23815168 |
| Abstract: | Preeclampsia monitored by the amount of proteinuria usually does not show amelioration during pregnancy. A 37-year-old nulliparous woman was admitted to our hospital at gestational week (GW) 24-1/7 due to rapid weight gain (6.2 kg/4 weeks) and oligohydramnios. Hypertension (151/91 mmHg) appeared atGW25-0/7 and proteinuria not detected at GW 24-0/7 became significant (0.55 g/day) at GW 25-2/7. During the 2 successive weeks after administration of betamethasone at 12 mg twice and transabdominal amnioinfusion with 250 mL of Ringer’s acetate solution at GW 25-3/7, generalized edema, proteinuria and thrombocytopenia markedly improved: bodyweight, 78.0 to 69.0 kg; proteinuria, from 7.1 to 1.3 g/day; and platelet count, from 111 to 230 ¥ 109/L. However, intrauterine infection accompanied by non-reassuring fetal status necessitated emergency cesarean section at GW 28-3/7. Extraordinary bodyweight gain can herald the occurrence of preeclampsia and this weight gain together with signs of preeclampsia can ameliorate even during pregnancy, although its mechanism is unclear. |
| Rights: | The definitive version is available at Wiley Online Library , www.wileyonlinelibrary.com. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/57865 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 水上 尚典
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