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Unusual clinical course of preeclampsia heralded by generalized edema

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J Obstet Gynaecol Res_39(11)_1538-1540.pdf529.71 kBPDFView/Open
Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/57865

Title: Unusual clinical course of preeclampsia heralded by generalized edema
Authors: Kojima, Takashi Browse this author
Yamada, Takahiro Browse this author →KAKEN DB
Yamada, Takashi Browse this author →KAKEN DB
Morikawa, Mamoru Browse this author →KAKEN DB
Cho, Kazutoshi Browse this author →KAKEN DB
Minakami, Hisanori Browse this author →KAKEN DB
Keywords: gestational edema
preeclampsia
thrombocytopenia
vascular permeability
Issue Date: Nov-2013
Publisher: Blackwell Publishing
Journal Title: Journal of Obstetrics and Gynaecology Research
Volume: 39
Issue: 11
Start Page: 1538
End Page: 1540
Publisher DOI: 10.1111/jog.12080
PMID: 23815168
Abstract: Preeclampsia monitored by the amount of proteinuria usually does not show amelioration during pregnancy. A 37-year-old nulliparous woman was admitted to our hospital at gestational week (GW) 24-1/7 due to rapid weight gain (6.2 kg/4 weeks) and oligohydramnios. Hypertension (151/91 mmHg) appeared atGW25-0/7 and proteinuria not detected at GW 24-0/7 became significant (0.55 g/day) at GW 25-2/7. During the 2 successive weeks after administration of betamethasone at 12 mg twice and transabdominal amnioinfusion with 250 mL of Ringer’s acetate solution at GW 25-3/7, generalized edema, proteinuria and thrombocytopenia markedly improved: bodyweight, 78.0 to 69.0 kg; proteinuria, from 7.1 to 1.3 g/day; and platelet count, from 111 to 230 ¥ 109/L. However, intrauterine infection accompanied by non-reassuring fetal status necessitated emergency cesarean section at GW 28-3/7. Extraordinary bodyweight gain can herald the occurrence of preeclampsia and this weight gain together with signs of preeclampsia can ameliorate even during pregnancy, although its mechanism is unclear.
Rights: The definitive version is available at Wiley Online Library , www.wileyonlinelibrary.com.
Type: article (author version)
URI: http://hdl.handle.net/2115/57865
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 水上 尚典

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