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Adenosquamous carcinoma of the conjunctiva: A case report

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Title: Adenosquamous carcinoma of the conjunctiva: A case report
Authors: Kase, Satoru Browse this author →KAKEN DB
Yoshikawa, Hiroshi Browse this author
Nakajima, Yutaka Browse this author
Noda, Mika Browse this author
Ishida, Susumu Browse this author →KAKEN DB
Keywords: adenosquamous carcinoma
Issue Date: Jun-2014
Publisher: Spandidos Publications
Journal Title: Oncology Letters
Volume: 7
Issue: 6
Start Page: 1941
End Page: 1943
Publisher DOI: 10.3892/ol.2014.2008
PMID: 24932264
Abstract: Adenosquamous carcinoma (ASC) is a rare form of malignancy which consists of two types of cell, including squamous cells and glandular-like cells. The current report presents the first known case of ASC in the conjunctiva and analyzes the histological findings. A 76-year-old female presented with right eyelid swelling in 2001. A right conjunctival tumor was noted and a biopsy was performed. Histologically, the tumor was diagnosed as a squamous cell carcinoma. The patient underwent radiotherapy, but the tumor rapidly relapsed. Subsequently, the patient underwent orbital exenteration. Histologically, the conjunctival tissues had been replaced with invasive tumor cells. A number of tumor cells demonstrated squamous differentiation with a keratinizing tendency, while other tumor cells exhibited mucin-producing activity with glandular formation. The conjunctival tumor was diagnosed as an ASC. At the time of writing, the patient is well without local recurrence or distant metastases. ASC typically exhibits aggressive biological behavior, and is associated with worse prognosis than conventional adenocarcinoma. Therefore, complete surgical excision is considered a key treatment for ASC of the conjunctiva.
Type: article
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 石田 晋

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