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Neuromyelitis optica spectrum disorders accompanying subarachnoid hemorrhage and reversible white matter lesions

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Title: Neuromyelitis optica spectrum disorders accompanying subarachnoid hemorrhage and reversible white matter lesions
Authors: Shirai, Shinichi Browse this author
Mito, Yasunori Browse this author
Nojo, Tatsuru Browse this author
Yaguchi, Hiroaki Browse this author
Takahashi, Toshiyuki Browse this author
Sato, Kazunori Browse this author
Hirotani, Makoto Browse this author →KAKEN DB
Kano, Takahiro Browse this author
Yabe, Ichiro Browse this author →KAKEN DB
Sasaki, Hidenao Browse this author →KAKEN DB
Keywords: Neuromyelitis optica
subarachnoid hemorrhage
posterior reversible encephalopathy syndrome
anti-Aquaporin 4 antibody
Issue Date: Jan-2014
Publisher: Wiley
Journal Title: Neurology and Clinical Neuroscience
Volume: 2
Issue: 1
Start Page: 10
End Page: 12
Publisher DOI: 10.1111/ncn3.68
Abstract: A 48-year-old man was admitted to Tomakomai City Hospital, Tomakomai, Japan, because of intractable hiccups and nausea, and orthostatic hypotension. Brain magnetic resonance imaging findings showed a dorsal medullary lesion. Respiratory failure occurred, and he underwent tracheotomy and mechanical ventilation when magnetic resonance imaging showed subarachnoid hemorrhage in addition to enlarged medullary lesions. Serum anti-aquaporin-4 antibody was positive and the cerebrospinal fluid was bloody. We diagnosed meuromyelitis optica spectrum disorders complicating subarachnoid hemorrhage. He was treated with a steroid. Although extensive white matter lesions occurred transiently, the patient was discharged from the hospital when he became able to walk with the use of the walker on the 52nd day. We suggest that the subarachnoid hemorrhage and transient white matter lesions were associated with vascular damage associated with the meuromyelitis optica spectrum disorders.
Type: article (author version)
Appears in Collections:医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 矢部 一郎

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