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Molecular epidemiology of paramyxoviruses in Zambian wild rodents and shrews
| Title: | Molecular epidemiology of paramyxoviruses in Zambian wild rodents and shrews |
| Authors: | Sasaki, Michihito Browse this author →KAKEN DB | | Muleya, Walter Browse this author | | Ishii, Akihiro Browse this author →KAKEN DB | | Orba, Yasuko Browse this author →KAKEN DB | | Hang'ombe, Bernard M. Browse this author | | Mweene, Aaron S. Browse this author | | Moonga, Ladslav Browse this author | | Thomas, Yuka Browse this author | | Kimura, Takashi Browse this author →KAKEN DB | | Sawa, Hirofumi Browse this author →KAKEN DB |
| Issue Date: | Feb-2014 |
| Publisher: | Society for General Microbiology |
| Journal Title: | Journal of General Virology |
| Volume: | 95 |
| Issue: | 2 |
| Start Page: | 325 |
| End Page: | 330 |
| Publisher DOI: | 10.1099/vir.0.058404-0 |
| PMID: | 24189618 |
| Abstract: | Rodents and shrews are known to harbour various viruses. Paramyxoviruses have been isolated from Asian and Australian rodents, but little is known about them in African rodents. Recently, previously unknown paramyxovirus sequences were found in South African rodents. To date, there have been no reports related to the presence and prevalence of paramyxoviruses in shrews. We found a high prevalence of paramyxoviruses in wild rodents and shrews from Zambia. Seminested reverse transcription-PCR assays were used to detect paramyxovirus RNA in 21% (96/ 462) of specimens analysed. Phylogenetic analysis revealed that these viruses were novel paramyxoviruses and could be classified as morbillivirus- and henipavirus-related viruses, and previously identified rodent paramyxovirus-related viruses. Our findings suggest the circulation of previously unknown paramyxoviruses in African rodents and shrews, and provide new information regarding the geographical distribution and genetic diversity of paramyxoviruses. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/57901 |
| Appears in Collections: | 人獣共通感染症国際共同研究所 (International Institute for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 佐々木 道仁
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