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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Dental Medicine / Faculty of Dental Medicine >
Peer-reviewed Journal Articles, etc >
Periodontal Healing by Implantation of Collagen Hydrogel-sponge Composite in One-wall Infrabony Defects in Beagle Dogs
| Title: | Periodontal Healing by Implantation of Collagen Hydrogel-sponge Composite in One-wall Infrabony Defects in Beagle Dogs |
| Authors: | Kato, Akihito Browse this author →KAKEN DB | | Miyaji, Hirofumi Browse this author →KAKEN DB | | Kosen, Yuta Browse this author | | Ishizuka, Ryosuke Browse this author | | Tokunaga, Keisuke Browse this author | | Inoue, Kana Browse this author | | Henmi, Masaru Browse this author | | Tanaka, Saori Browse this author →KAKEN DB | | Sugaya, Tsutomu Browse this author →KAKEN DB | | Kawanami, Masamitsu Browse this author →KAKEN DB |
| Keywords: | collagen hydrogel sponge composite | | scaffold | | periodontal wound healing |
| Issue Date: | 30-Sep-2010 |
| Publisher: | 日本再生歯科医学会 |
| Journal Title: | Journal of Oral Tissue Engineering |
| Volume: | 8 |
| Issue: | 1 |
| Start Page: | 39 |
| End Page: | 46 |
| Abstract: | The purpose of this study was to evaluate the effect of implanted collagen hydrogel-sponge composite on periodontal wound healing. One-wall infrabony defects (depth: 5 mm; width: 3 mm) were surgically created in three beagle dogs. The exposed root surface was planed and demineralized with EDTA. In the experimental group, the defects were filled with collagen hydrogel-sponge composite. Conversely, no collagen hydrogel-sponge composite was applied to defects in the control group. Histomorphometric parameters were evaluated four weeks after surgery. In the experimental group, regeneration of alveolar bone and cementum was frequently observed. Periodontal ligament tissue was reestablished between the alveolar bone and cementum. New bone height, new bone area, new cementum and new periodontal ligament in the experimental group were significantly greater than those in the control group (p < 0.05). These findings suggest that implanted collagen hydrogel-sponge composite facilitates periodontal wound healing in one-wall infrabony defects in beagle dogs. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/59076 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 加藤 昭人
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