|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine >
Peer-reviewed Journal Articles, etc >
Pathogenicity of border disease virus FNK2012-1 strain isolated from a pig in the natural host, sheep
This item is licensed under:Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported
| Title: | Pathogenicity of border disease virus FNK2012-1 strain isolated from a pig in the natural host, sheep |
| Authors: | Tamura, Tomokazu Browse this author | | Mine, Junki Browse this author | | Torii, Shiho Browse this author | | Fujimoto, Yuri Browse this author | | Okamatsu, Masatoshi Browse this author →KAKEN DB | | Sakoda, Yoshihiro Browse this author →KAKEN DB |
| Keywords: | border disease virus | | host | | pathogenicity | | sheep |
| Issue Date: | Mar-2015 |
| Publisher: | The Journal of Veterinary Medical Science |
| Journal Title: | Journal of veterinary medical science |
| Volume: | 77 |
| Issue: | 3 |
| Start Page: | 341 |
| End Page: | 343 |
| Publisher DOI: | 10.1292/jvms.14-0434 |
| Abstract: | A first isolation of border disease virus (BDV) in Japan was from a pig on a farm without keeping any ruminants. Our previous study showed that this BDV, termed the FNK2012-1 strain, replicated inefficiently in swine-derived cells compared with those of ruminant origin. Pigs inoculated with this virus showed neither clinical symptoms nor viremia. In this study, we evaluated the pathogenicity of the FNK2012-1 strain in sheep, its natural host. The inoculated sheep showed clinical symptoms and transient viremia. Seroconversion was observed in the inoculated sheep. These results suggest that the FNK2012-1 strain was introduced from sheep and has not yet adapted to swine. Therefore, surveillance of border disease in Japan is necessary among both the swine and ruminant populations. |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/3.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/59104 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
Submitter: 田村 友和
|
