Title: | Lymph Node Metastasis in T4 Maxillary Sinus Squamous Cell Carcinoma : Incidence and Treatment Outcome |
Authors: | Homma, Akihiro Browse this author →KAKEN DB |
Hayashi, Ryuichi Browse this author |
Matsuura, Kazuto Browse this author |
Kato, Kengo Browse this author |
Kawabata, Kazuyoshi Browse this author |
Monden, Nobuya Browse this author |
Hasegawa, Yasuhisa Browse this author |
Onitsuka, Tetsuro Browse this author |
Fujimoto, Yasushi Browse this author |
Iwae, Shigemichi Browse this author |
Okami, Kenji Browse this author |
Matsuzuka, Takashi Browse this author |
Yoshino, Kunitoshi Browse this author |
Nibu, Ken-ichi Browse this author |
Kato, Takakuni Browse this author |
Nishino, Hiroshi Browse this author |
Asakage, Takahiro Browse this author |
Ota, Ichiro Browse this author |
Kitamura, Morimasa Browse this author |
Kubota, Akira Browse this author |
Ueda, Tsutomu Browse this author |
Ikebuchi, Kaichiro Browse this author |
Watanabe, Akihito Browse this author |
Fujii, Masato Browse this author |
Issue Date: | May-2014 |
Publisher: | Springer |
Journal Title: | Annals of Surgical Oncology |
Volume: | 21 |
Issue: | 5 |
Start Page: | 1706 |
End Page: | 1710 |
Publisher DOI: | 10.1245/s10434-014-3544-6 |
PMID: | 24554063 |
Abstract: | The purpose of this study was to evaluate the incidence of lymph node metastasis among patients with T4 maxillary sinus squamous cell carcinoma (MS-SCC) as well as the delayed metastasis rate and the treatment outcome for untreated N0 neck in patients with T4 MS-SCC. Consecutive series of all patients (n = 128) with previously untreated T4 maxillary sinus SCC between 2006 and 2007 were obtained from 28 institutions belonging to or cooperating in the Head and Neck Cancer Study Group of the Japan Clinical Oncology Group. Of the 128 patients, 28 (21.9 %) had lymph node metastasis, and six patients (4.7 %) had distant metastasis at diagnosis. Among the 111 patients who were treated with curative intent, 98 had clinically N0 neck disease and did not receive prophylactic neck irradiation. A total of 11 patients (11.2 %) subsequently developed evidence of lymph node metastasis, of whom eight were among the 83 patients with an N0 neck and had not received elective neck treatment. There were 15 patients who received an elective neck dissection as part of the initial treatment, of whom three had pathologically positive for lymph node metastases. Of 11 patients, six patients with nonlateral retropharyngeal lymph node metastasis without primary or distant disease were successfully salvaged. This study identified the incidence of lymph node metastasis among patients with T4 MS-SCC as well as the delayed metastasis rate and the treatment outcome for untreated N0 neck in patients with T4 MS-SCC. These results will be of assistance in selecting treatment strategy for T4 MS-SCC in the future. |
Rights: | The original publication is available at www.springerlink.com |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/59107 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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